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Fulminant hepatic failure as the initial presentation of acute autoimmune hepatitis  William R Kessler, Oscar W Cummings, George Eckert, Naga Chalasani,

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Presentation on theme: "Fulminant hepatic failure as the initial presentation of acute autoimmune hepatitis  William R Kessler, Oscar W Cummings, George Eckert, Naga Chalasani,"— Presentation transcript:

1 Fulminant hepatic failure as the initial presentation of acute autoimmune hepatitis 
William R Kessler, Oscar W Cummings, George Eckert, Naga Chalasani, Lawrence Lumeng, Paul Y Kwo  Clinical Gastroenterology and Hepatology  Volume 2, Issue 7, Pages (July 2004) DOI: /S (04)

2 Figure 1 Acute autoimmune hepatitis. (A and B) There is marked zone 3 hepatocyte necrosis and collapse associated with a mixed chronic inflammatory cell infiltrate including eosinophils, plasma cells and lymphocytes. (C) The portal tract (right hand corner) shows no inflammation or fibrosis (trichrome stain). Clinical Gastroenterology and Hepatology 2004 2, DOI: ( /S (04) )

3 Figure 2 Chronic autoimmune hepatitis. The portal tract is predominantly expanded by a chronic inflammatory cell infiltrate. (A) There is an interface hepatitis (B) with small buds of type-one collagen extending into the lobule (periportal fibrosis). Clinical Gastroenterology and Hepatology 2004 2, DOI: ( /S (04) )


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