1. Learning Target
Explain how failure to maintain homeostasis can result in disease or death
HW: Read Q1-3 p. 488

2. True or False: Each body system works in isolation
Question
True or False: Each body system works in isolation

3. False
Body systems are interrelated and work through a series of feedback systems
Can you name two that work together?

4. Homeostasis
Maintence of constant internal environment by making adjustments to external and internal environment

5. Negative feedback
The reaction has an opposite effect on the change in environment
Ex: Exercise increase cellular respiration= more CO2 in blood- respiration- Breathing rate increases to reduce CO2 levels .

6. A negative feedback system is one that Maintains Homeostasis.

7. Positive Feedback the change will continue to increase in one direction until something happens in the body to stop it.

8. A series or reaction will increase contractions, dialation etc
Child Birth
A series or reaction will increase contractions, dialation etc

9. The feedback cycle

10. Glucose: Insulin and Glucagon
The receptors of the pancreas are responsible for monitoring glucose levels in the blood.

12. Blood Glucose Level
Pancreatic Hormones regulate blood sugar level before and after meals.
Islets; clusters of cells in pancreas
Alphasecrete GLUCAGON – increases sugar
Beta secrete INSULIN – decreases sugar

13. What Happens? Between meals
Blood glucose lowPancreas secretes glucagonLiver changes glycogen to glucoseglucose sent to target tissues
After a meal
Blood glucose highPancreas secretes insulinGlucose goes to the Liver(Glygogen) and goes to Target tissues

15. Fight or Flight
In emergencies, adrenaline is released by the body to override the homeostatic control of glucose. This is done to promote the breakdown of glycogen into glucose to be used in the emergency. These emergencies are often known as 'fight or flight reactions'.

16. Fight or Flight
Adrenaline is secreted by the adrenal glands. The secretion of it leads to increased metabolism, breathing and heart rate. Once the emergency is over, and adrenaline levels drop, the homeostatic controls are once again back in place

17. Thermoregulation

19. ENGAGE
View the video clip, “The Search for Answers” beginning at 2:50.
The Search for Answers

20. EXPLORE
Compare the level of serotonin and serontonin receptors. Stop the video at 3:50, 3:56, and 4:03

21. EXPLAIN 1. What is the role of serotonin?
2. What is the effect of high levels of serotonin on the body?
3. Explain how the body attempts to regulate serotonin levels?
4. Relate serotonin regulation to anorexia nervosa.

22. Role Play: The Rise and Fall of Glucose
ELABORATE
Role Play: The Rise and Fall of Glucose

23. How does the body keep from overheating? How does the body keep warm?
ELABORATE
How does the body keep from overheating?
How does the body keep warm?

24. EVALUATE
Produce a sketch or graph and describe a negative feedback system.
Produce a labeled sketch of thermal regulation in humans.
Summarize the regulation of blood glucose

25. Calcium and glucose levels
Concept Map
The Endocrine System
regulates
Growth
Water balance
Reproduction
Metabolism
Calcium and glucose levels
Response to stress
by means of the
by means of the
by means of the
by means of the
by means of the
by means of the
Pituitary
Ovaries
Testes
Thyroid
Pancreas
Adrenals
Parathyroids