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Chapter 27: Drugs for Lipid Disorders

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1 Chapter 27: Drugs for Lipid Disorders
DISCUSSION POINTS Chapter 27: Drugs for Lipid Disorders Pharmacology for Nurses: A Pathophysiologic Approach, 1/e Michael Patrick Adams Dianne L. Josephson Leland Norman Holland, Jr. Copyright ©2005 by Pearson Education, Inc. Upper Saddle River, New Jersey All rights reserved.

2 Types of Lipids - Triglycerides - Phospholipids - Steroids
Pharmacology for Nurses: A Pathophysiologic Approach, 1/e Michael Patrick Adams Dianne L. Josephson Leland Norman Holland, Jr. Copyright ©2005 by Pearson Education, Inc. Upper Saddle River, New Jersey All rights reserved.

3 - High-density lipoprotein (HDL) - Low-density lipoprotein (LDL)
Lipoproteins - High-density lipoprotein (HDL) - Low-density lipoprotein (LDL) - Very low-density lipoprotein (VLDL) Pharmacology for Nurses: A Pathophysiologic Approach, 1/e Michael Patrick Adams Dianne L. Josephson Leland Norman Holland, Jr. Copyright ©2005 by Pearson Education, Inc. Upper Saddle River, New Jersey All rights reserved.

4 Discuss the teaching needs for the patient in the following scenario: A client has been taking atorvastatin calcium (Lipitor) 80 mg daily for eight weeks. The blood lipid levels are still elevated. The physician finds out the client is eating a lot of foods high in cholesterol and saturated fats. The client states, “I thought that ‘pill’ was to take care of everything.” Pharmacology for Nurses: A Pathophysiologic Approach, 1/e Michael Patrick Adams Dianne L. Josephson Leland Norman Holland, Jr. Copyright ©2005 by Pearson Education, Inc. Upper Saddle River, New Jersey All rights reserved.

5 Discuss the rationale for patients requiring an antihyperlipidemic agent even though they have reduced their dietary intake of cholesterol and saturated fats. Pharmacology for Nurses: A Pathophysiologic Approach, 1/e Michael Patrick Adams Dianne L. Josephson Leland Norman Holland, Jr. Copyright ©2005 by Pearson Education, Inc. Upper Saddle River, New Jersey All rights reserved.

6 HMG CoA reductase inhibitor - Best time of day to take
- Reason for this timing Pharmacology for Nurses: A Pathophysiologic Approach, 1/e Michael Patrick Adams Dianne L. Josephson Leland Norman Holland, Jr. Copyright ©2005 by Pearson Education, Inc. Upper Saddle River, New Jersey All rights reserved.

7 The rationale why patients should not self-medicate with OTC niacin to lower blood lipid levels
Pharmacology for Nurses: A Pathophysiologic Approach, 1/e Michael Patrick Adams Dianne L. Josephson Leland Norman Holland, Jr. Copyright ©2005 by Pearson Education, Inc. Upper Saddle River, New Jersey All rights reserved.

8 The reasons that patients must wait a month or more to see the effects of lipid-lowering agents
Pharmacology for Nurses: A Pathophysiologic Approach, 1/e Michael Patrick Adams Dianne L. Josephson Leland Norman Holland, Jr. Copyright ©2005 by Pearson Education, Inc. Upper Saddle River, New Jersey All rights reserved.

9 The rationale behind why HMG CoA reductase inhibitors are contraindicated in patients with liver dysfunction Pharmacology for Nurses: A Pathophysiologic Approach, 1/e Michael Patrick Adams Dianne L. Josephson Leland Norman Holland, Jr. Copyright ©2005 by Pearson Education, Inc. Upper Saddle River, New Jersey All rights reserved.


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