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Cold retrograde cerebral perfusion improves cerebral protection during moderate hypothermic circulatory arrest: A long-term study in a porcine model 

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Presentation on theme: "Cold retrograde cerebral perfusion improves cerebral protection during moderate hypothermic circulatory arrest: A long-term study in a porcine model "— Presentation transcript:

1 Cold retrograde cerebral perfusion improves cerebral protection during moderate hypothermic circulatory arrest: A long-term study in a porcine model  Vesa Anttila, MDa, Kai Kiviluoma, MD, PhDb, Matti Pokela, MSa, Jussi Rimpiläinen, MDa, Minna Mäkiranta, MScc, Ville Jäntti, MD, PhDc, Jorma Hirvonen, MD, PhDd, Tatu Juvonen, MD, PhDa  The Journal of Thoracic and Cardiovascular Surgery  Volume 118, Issue 5, Pages (November 1999) DOI: /S (99) Copyright © 1999 Mosby, Inc. Terms and Conditions

2 Fig. 1 Rectal temperatures of 12 pigs undergoing 45 minutes of either HCA or cold RCP with head packed in ice during the experiment. Values are shown as medians with interquartile ranges. The Journal of Thoracic and Cardiovascular Surgery  , DOI: ( /S (99) ) Copyright © 1999 Mosby, Inc. Terms and Conditions

3 Fig. 2 Daily scores indicating behavioral recovery after interventions. A score of 8 or 9 indicates essentially complete recovery, lower scores indicate substantial impairment, and a score of zero indicates coma or death. Behavioral scores showed a significant difference between recovery after RCP and HCA with heads packed in ice on day 7 (P = .04). The line is interrupted at the point of death. The Journal of Thoracic and Cardiovascular Surgery  , DOI: ( /S (99) ) Copyright © 1999 Mosby, Inc. Terms and Conditions

4 Fig. 3 Total histopathologic scores of 12 pigs undergoing 45 minutes of either hypothermic HCA or cold RCP with heads packed in ice. The Journal of Thoracic and Cardiovascular Surgery  , DOI: ( /S (99) ) Copyright © 1999 Mosby, Inc. Terms and Conditions

5 Fig. 4 Medians with interquartile ranges for total EEG burst ratios (relative to baseline) of 12 pigs undergoing 45 minutes of either HCA or cold RCP with heads packed in ice. The Journal of Thoracic and Cardiovascular Surgery  , DOI: ( /S (99) ) Copyright © 1999 Mosby, Inc. Terms and Conditions

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