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Prognostic Impact of Margin Distance and Tumor Spread Through Air Spaces in Limited Resection for Primary Lung Cancer  Kyohei Masai, MD, Hiroyuki Sakurai,

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Presentation on theme: "Prognostic Impact of Margin Distance and Tumor Spread Through Air Spaces in Limited Resection for Primary Lung Cancer  Kyohei Masai, MD, Hiroyuki Sakurai,"— Presentation transcript:

1 Prognostic Impact of Margin Distance and Tumor Spread Through Air Spaces in Limited Resection for Primary Lung Cancer  Kyohei Masai, MD, Hiroyuki Sakurai, MD, Aoi Sukeda, MD, Shigeki Suzuki, MD, Keisuke Asakura, MD, Kazuo Nakagawa, MD, Hisao Asamura, MD, Shun-ichi Watanabe, MD, Noriko Motoi, MD, PhD, Nobuyoshi Hiraoka, MD, PhD  Journal of Thoracic Oncology  Volume 12, Issue 12, Pages (December 2017) DOI: /j.jtho Copyright © 2017 International Association for the Study of Lung Cancer Terms and Conditions

2 Figure 1 Representative images of tumor spread through air spaces (STAS) in adenocarcinoma (A–D), squamous cell carcinoma (E and F), and small cell carcinoma (G and H). STAS was found as a single cell (B), small cell cluster (B and H), or large nests (D and H). STAS was located near (C and E) or far (A and G) from the edge of the tumor. The right column images (B, D, F, and H) are the high-power views of the boxed areas. The asterisk indicates at least one free alveolar space between the STAS and main tumor. (A and E) Hematoxylin and eosin stain. Scale bars: 0.2 mm (A and E), 0.05 mm (B, D, and H), 0.5 mm (C and G), and 0.1 mm (F). Journal of Thoracic Oncology  , DOI: ( /j.jtho ) Copyright © 2017 International Association for the Study of Lung Cancer Terms and Conditions

3 Figure 2 Relapse-free survival curves for local recurrence of patients undergoing limited resection for primary lung cancer according to margin distance (A and B) and tumor spread through air spaces (STAS) (C). Journal of Thoracic Oncology  , DOI: ( /j.jtho ) Copyright © 2017 International Association for the Study of Lung Cancer Terms and Conditions

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