1. Nat. Rev. Neurol. doi:10.1038/nrneurol.2015.157
Figure 2 Serial T1-weighted MRI scans in a patient with multiple sclerosis
Figure 2 | Serial T1-weighted MRI scans in a patient with multiple sclerosis. a | Baseline scan. b–d | Regular scans over a 6-year follow-up period. Disease progression can be seen in the form of the increasing size of ventricular and subarachnoid spaces. These changes reflect brain volume loss over time, indicating progressive neurodegeneration.
Wattjes, M. P. et al. (2015) MAGNIMS consensus guidelines on the use of MRI in multiple sclerosis—establishing disease prognosis and
monitoring patients
Nat. Rev. Neurol. doi: /nrneurol