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Cerebrospinal Fluid Markers of Brain Injury, Inflammation, and Blood-Brain Barrier Dysfunction in Cardiac Surgery  Björn Reinsfelt, MD, PhD, Sven-Erik.

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Presentation on theme: "Cerebrospinal Fluid Markers of Brain Injury, Inflammation, and Blood-Brain Barrier Dysfunction in Cardiac Surgery  Björn Reinsfelt, MD, PhD, Sven-Erik."— Presentation transcript:

1 Cerebrospinal Fluid Markers of Brain Injury, Inflammation, and Blood-Brain Barrier Dysfunction in Cardiac Surgery  Björn Reinsfelt, MD, PhD, Sven-Erik Ricksten, MD, PhD, Henrik Zetterberg, MD, PhD, Kaj Blennow, MD, PhD, Johan Fredén-Lindqvist, MD, Anne Westerlind, MD, PhD  The Annals of Thoracic Surgery  Volume 94, Issue 2, Pages (August 2012) DOI: /j.athoracsur Copyright © 2012 The Society of Thoracic Surgeons Terms and Conditions

2 Fig 1 Individual data on the intraoperative occurrence of microembolic signals. (CPB = cardiopulmonary bypass.) The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2012 The Society of Thoracic Surgeons Terms and Conditions

3 Fig 2 (A)-(E) Individual data on preoperative and postoperative levels of the cerebrospinal fluid (CSF) to (A) serum albumin ratio, (B) interleukin-6 (IL-6), (C) interleukin-8 (IL-8), (D) S-100B, and (E) glial fibrillary acidic protein (GFAP). The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2012 The Society of Thoracic Surgeons Terms and Conditions

4 Fig 3 Individual data on preoperative and postoperative levels of the cerebrospinal fluid (CSF): (A) neuron-specific enolase (NSE), (B) total tau (T-tau), and (C) neurofilament light chain protein (NF-L). The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2012 The Society of Thoracic Surgeons Terms and Conditions

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