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Randomized trial of intermittent antegrade warm blood versus cold crystalloid cardioplegia  Luc M Jacquet, MD, Philippe H Noirhomme, MD, Michel J Van.

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Presentation on theme: "Randomized trial of intermittent antegrade warm blood versus cold crystalloid cardioplegia  Luc M Jacquet, MD, Philippe H Noirhomme, MD, Michel J Van."— Presentation transcript:

1 Randomized trial of intermittent antegrade warm blood versus cold crystalloid cardioplegia 
Luc M Jacquet, MD, Philippe H Noirhomme, MD, Michel J Van Dyck, MD, Gebrin A El Khoury, MD, Amin J Matta, MD, Martin J Goenen, MD, Robert A Dion, MD  The Annals of Thoracic Surgery  Volume 67, Issue 2, Pages (February 1999) DOI: /S (98)

2 Fig 1 Comparison of hemodynamic data between the two study groups: (A) cardiac output, (B) mean pulmonary artery pressure, (C) central venous pressure, and (D) right ventricular stroke work index (R.V.S.W.I.). Open bars indicate cold cardioplegia; solid bars indicate normothermic cardioplegia. (T-1 = induction of anesthesia; T0 = arrival in intensive care unit; T1 = 4 hours after operation; T2 = 8 hours after operation; T3 = postoperative day 1; T4 = postoperative day 2; ∗ = p < 0.05.) The Annals of Thoracic Surgery  , DOI: ( /S (98) )

3 Fig 2 Comparison of markers of cardiac cell damage in the two study groups: (A) aspartate aminotransferase (ASAT); (B) creatine kinase-MB mass assay (CK-MB); (C) cardiac troponin I. (∗ = p < 0.05; ∗∗ = p < 0.01; other abbreviations as in Fig 1. The Annals of Thoracic Surgery  , DOI: ( /S (98) )

4 Fig 3 Comparison of cardiac troponin I (cTn-I) levels in patients without electrical countershock. (∗ = p < 0.05; ∗∗ = p < 0.01; other abbreviations as in Fig 1.) The Annals of Thoracic Surgery  , DOI: ( /S (98) )

5 Fig 4 Comparison of mean area under cardiac troponin I (cTn-I) curve until day 2 after operation. The Annals of Thoracic Surgery  , DOI: ( /S (98) )

6 Fig 5 Comparison of cumulative fluid balance until postoperative day 2. (O.R. = in the operating room; ∗ = p < 0.01; other abbreviations as in Fig 1.) The Annals of Thoracic Surgery  , DOI: ( /S (98) )


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