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Figure 2 from Sancho et al.

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Presentation on theme: "Figure 2 from Sancho et al."— Presentation transcript:

1 Targeting cancer stem cells through inhibition of mitochondrial function
Figure 2 from Sancho et al. British Journal of Cancer Advance Online Publication 24 May 2016 doi: /bjc Several approaches exist to target Eph receptors. Kinase inactivating strategies include kinase inhibitors or blocking peptides or antibodies. Kinase activating strategies include ligand stimulation, activating antibodies or ligand peptide mimetics Strategies to deliver toxic payloads following receptor activation and internalisation include coupling of cytotoxic agents or radionuclides to Eph monoclonal antibodies. © 2016 Cancer Research UK.


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