Presentation is loading. Please wait.

Presentation is loading. Please wait.

The role of mitochondrial activity in female fertility and assisted reproductive technologies: overview and current insights  Gustavo Nardini Cecchino,

Published byBuck Curtis Modified over 5 years ago

Similar presentations

Presentation on theme: "The role of mitochondrial activity in female fertility and assisted reproductive technologies: overview and current insights  Gustavo Nardini Cecchino,"— Presentation transcript:

1 The role of mitochondrial activity in female fertility and assisted reproductive technologies: overview and current insights  Gustavo Nardini Cecchino, Emre Seli, Eduardo Leme Alves da Motta, Juan Antonio García-Velasco  Reproductive BioMedicine Online  Volume 36, Issue 6, Pages (June 2018) DOI: /j.rbmo Copyright © 2018 Reproductive Healthcare Ltd. Terms and Conditions

2 Figure 1 Electron transport chain (ETC) in the inner mitochondrial membrane. Reactions in complexes I, III and IV result in a stream of protons into the mitochondrial intermembrane space. In complex V, the energy generated by the mobilization of protons back into the mitochondrial matrix results in ATP synthesis by phosphorylation. NADH: nicotinamide adenine dinucleotide hydride, NAD+: nicotinamide adenine dinucleotide, CoQ10: coenzyme Q10, FADH2: flavin adenine dinucleotide hydride, FAD: flavin adenine dinucleotide, Cytc: cytochrome c, ADP: adenosine diphosphate; ATP: adenosine triphosphate. Reproductive BioMedicine Online  , DOI: ( /j.rbmo ) Copyright © 2018 Reproductive Healthcare Ltd. Terms and Conditions

3 Figure 2 Oxidative stress-related factors and pathologies with a negative impact on female reproductive processes and assisted reproductive technology (ART) outcomes. Technical issues are well documented with the laboratory manipulation of gametes and embryos. There is increasing evidence that lifestyle habits and specific pathologies that generate oxidative damage also affect the female reproductive system and, ultimately, the success of ART. Reproductive BioMedicine Online  , DOI: ( /j.rbmo ) Copyright © 2018 Reproductive Healthcare Ltd. Terms and Conditions

Download ppt "The role of mitochondrial activity in female fertility and assisted reproductive technologies: overview and current insights  Gustavo Nardini Cecchino,"

Similar presentations

Topic 8.1 Cell Respiration (HL).

Topic 8.1 Cell Respiration (HL).
Cellular Respiration: The Release of Energy in Cells.

Cellular Respiration: The Release of Energy in Cells.
Chapter 3 Energy Transformation Objectives: Review processes and reactions important to metabolic energy transformation Recall the rules that govern energy.

Chapter 3 Energy Transformation Objectives: Review processes and reactions important to metabolic energy transformation Recall the rules that govern energy.
The versatility of catabolism

The versatility of catabolism
Lecture 5 Proton Pumping and ATP Synthesis Mechanisms.

Lecture 5 Proton Pumping and ATP Synthesis Mechanisms.
OXIDATION PHOSPHORYLATION-1 BIOC 460 - DR. TISCHLER LECTURE 28.

OXIDATION PHOSPHORYLATION-1 BIOC DR. TISCHLER LECTURE 28.
Krebs Cycle state that the Krebs cycle takes place in the mitochondrial matrix; outline the Krebs cycle, with reference to the formation of citrate from.

Krebs Cycle state that the Krebs cycle takes place in the mitochondrial matrix; outline the Krebs cycle, with reference to the formation of citrate from.
ADP, ATP and Cellular Respiration

ADP, ATP and Cellular Respiration
Cellular Respiration Chapter 9.

Cellular Respiration Chapter 9.
Metabolism and Energy Production

Metabolism and Energy Production
Stages of Metabolism.

Stages of Metabolism.
AP Biology Cellular Respiration Part 2. Is Oxygen present?

AP Biology Cellular Respiration Part 2. Is Oxygen present?
Cellular Respiration.

Cellular Respiration.
Energy and Life 1 Living things need energy to survive comes from food energy in most food comes from the sun Plants use light energy from the sun to produce.

Energy and Life 1 Living things need energy to survive comes from food energy in most food comes from the sun Plants use light energy from the sun to produce.
RESPIRATION & COUPLED REACTIONS. THE ELECTRON TRANSPORT CHAIN (ETC) Coupling the oxidation of food to the synthesis of ATP Oxidation Is a Loss of electrons.

RESPIRATION & COUPLED REACTIONS. THE ELECTRON TRANSPORT CHAIN (ETC) Coupling the oxidation of food to the synthesis of ATP Oxidation Is a Loss of electrons.
Objective: You will be able to compare and contrast the equations of respiration. Do Now: Read p. 221 What is the most important use of food?

Objective: You will be able to compare and contrast the equations of respiration. Do Now: Read p. 221 What is the most important use of food?
Www.soran.edu.iq M. Saadatian Cellular respiration 1.

M. Saadatian Cellular respiration 1.
Electron Transport Occurs on the Cristae or intermembrane of Mitochondria.

Electron Transport Occurs on the Cristae or intermembrane of Mitochondria.
NADH NAD + H+H+ H+H+ H+H+ H+H+ H+H+ H+H+ H+H+ H+H+ H+H+ H+H+ H+H+ H+H+ H+H+ H+H+ O2O2 O H2OH2O H+H+ H+H+ H+H+ H+H+ H+H+ H+H+ H+H+ Electron Transport ATP.

NADH NAD + H+H+ H+H+ H+H+ H+H+ H+H+ H+H+ H+H+ H+H+ H+H+ H+H+ H+H+ H+H+ H+H+ H+H+ O2O2 O H2OH2O H+H+ H+H+ H+H+ H+H+ H+H+ H+H+ H+H+ Electron Transport ATP.
Outer membrane inner membrane matrix red = respiratory chain proteins green = ATP synthases Figure 1. Location of enzymes involved in oxidative phosphorylation.

Outer membrane inner membrane matrix red = respiratory chain proteins green = ATP synthases Figure 1. Location of enzymes involved in oxidative phosphorylation.

Similar presentations

Ads by Google