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Managing Polycythemia Vera in the Community Setting

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Presentation on theme: "Managing Polycythemia Vera in the Community Setting"— Presentation transcript:

1 Managing Polycythemia Vera in the Community Setting

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3 Polycythemia Vera Introduction

4 2016 WHO Diagnostic Criteria for PV Summary of Changes to 2008 Criteria

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7 Is BM Biopsy Always Required?

8 Progression of PV Is Genetic Testing Useful At This Time?

9 Prognostic Impact of Next-Generation Sequencing

10 Symptom Burden in Patients With PV

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12 Treatment Goals Patient vs Physician

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14 Cytoreductive Therapy Hydroxyurea

15 Cytoreductive Therapy Long-Acting IFN-α

16 HCT ≥45% Increases The Risk of CV-Related Death or Thrombosis

17 Management Summary of Patient With PV

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19 Resistance or Intolerance to HU in a Study of 890 Patients With PV

20 HU Intolerance in Patients With PV Symptoms and QoL

21 Advantages of Long Acting IFN-α Therapy for PV

22 Ruxolitinib

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24 RESPONSE Thromboembolic Adverse Events at Week 80

25 RESPONSE Other Adverse Events of Interest

26 How to Address Adverse Events

27 Concluding Remarks

28 Abbreviations

29 Abbreviations (cont)


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