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Introduction Antiplatelet Agents ADP Receptor Antagonists.

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Presentation on theme: "Introduction Antiplatelet Agents ADP Receptor Antagonists."— Presentation transcript:

1

2

3 Introduction

4 Antiplatelet Agents

5 ADP Receptor Antagonists

6 CURE Reduction in Cardiovascular Events With Clopidogrel

7 TRITON-TIMI 38 Risk Reduction Prasugrel vs Clopidogrel

8 PLATO Major Events: Ticagrelor vs Clopidogrel

9 Onset of Action

10 Randomized Trials of Antiplatelet Agents TRITON-TIMI 38 and PLATO

11 TRANSLATE-ACS

12 After the Patient Goes Home…

13 Antiplatelet Use After PCI

14 Hospitalized Bleeding

15 TRANSLATE-ACS Factors Associated With In-hospital Switch From 1st- to 2nd-generation ADP Receptor Inhibitor

16 TRANSLATE-ACS Factors Associated With In-hospital Switch From 2nd to 1st -generation ADP Receptor Inhibitor

17 Genetic Effects on Pharmacokinetic and Pharmacodynamic Responses to Clopidogrel

18 TRITON-TIMI 38 Risk Reduction: Prasugrel vs Clopidogrel

19 TRANSLATE-POPS Design

20 POPS – Change in Treatment

21 Summary

22 Abbreviations

23 Abbreviations (cont)

24 References

25 References (cont)

26 References (cont)

27 References (cont)


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