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Lipid Clinic Challenge

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Presentation on theme: "Lipid Clinic Challenge"— Presentation transcript:

1 Lipid Clinic Challenge

2 Who is Vulnerable and Why

3 JUPITER Increased Incidence of T2D With Rosuvastatin

4 Hypotheses

5 T2D Risk Increases With Statin Potency Meta-Analysis of 5 Clinical Trials

6 WOSCOPS Pravastatin Reduction in LDL-C/Reduced CAD by 30%

7 Statins and the Development of Diabetes[a,b]

8 JUPITER Rosuvastatin Therapy and Diabetes Risk[a,b]

9 Obesity and Metabolic Syndrome

10 Analysis of 3 Atorvastatin Trials (TNT, SPARCL, and IDEAL)

11 Don't Just Blame Statins

12 2013 ACC/AHA Cholesterol Guidelines Statin Initiation Recommendations

13 REAL-CAD: Primary Endpoint CV Death/MI/Ischemic Stroke/UA

14 J-PREDICT Primary Outcome: Cumulative Incidence of Diabetes

15 ABCA1: A Very Important Transmembrane HDL Binding Protein

16 Pitavastatin: No Elevation in Serum Glucose

17 Managing Cardiovascular Risk

18 Hepatic Steatosis and Insulin Resistance

19 Effects of Pitavastatin on Insulin Sensitivity and Liver Fat

20 Case Study: Patient With Obesity With Hypertension and Dyslipidemia

21 Case Study: Patient With Obesity With Hypertension and Dyslipidemia

22 Many Issues at Play: Education is Needed

23 It Takes a Team

24 Abbreviations

25 Abbreviations (cont)


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