1. Statin Selection Aimed to Reduce New-Onset DM Risk:

3. Our Goals Are to Improve Our Knowledge of:

4. Statins and New-Onset T2D: RCT Publication Timeline

5. JUPITER: Rosuvastatin Therapy and Diabetes Risk

6. Statin Diabetogenicity

7. Statin Diabetogenicity (cont)

8. How Statins Lower Cholesterol: The Mechanism

9. Apoptosis of Beta Cells

10. Clinical Risk Factors

11. Hypothesis History Reversed

12. Certain Statins Increase the Risk of New-Onset T2D

13. Risk of New-Onset T2D With Statin by Age

14. HMG-CoA Reductace

15. J-PREDICT Study Design

16. Primary Outcome: Cumulative Incidence of Diabetes

17. Pitavastatin and Glucose Endpoint

18. Lifestyle

19. Patient Education -- Team Approach

20. Thoughtful Statin Consideration

21. Summary

22. Summary (cont)

23. Abbreviations