1. APPLICATION TO THE HADROTHERAPY FOR OCULAR MELANOMAS
In this talk I would like to explain the reasons are bring us to work with G4 and the goals we wold like to obtain with its use.
We are the only italian prothontherapy center and actually we treated 15 patients
G.A. Pablo Cirrone
Qualified Medical Physicist and PhD Student
University of Catania and Laboratori Nazionali del Sud INFN, Italy

2. LNS Superconducting Cyclotron in Catania is the unique machine in in Italy and South Europe used for protontherapy

3. Depth doses in radiotherapy: single fields

4. Why clinical proton beams?
penetration depth is well-defined and adjustable
most energy at end-of -range
protons travel in straight lines
dose to normal tissue minimised
no dose beyond target

5. MEDICAL APPLICATION OF THE CATANA FACILITY
Choroidal Melanoma
% successfully treating with proton beams
About 300 new cases for year in Italy
In the world 5000 patients have been already treated with proton beams
Age related subfoveal macular degenerations with subretinal neovascular membrane
This is the main cause of third age blindness in EC countries
It is a “social disease” for EC
INFN - LNS

6. LAYOUT OF LNS 0 ° respect the switching magnet
PRESENT TREATMENT ROOM
0 ° respect the switching magnet
80 meter after extraction
3 m proton beam line
LAYOUT OF LNS

7. Scattering system Modulator & Range shifter Ligth field
Laser
Scattering system
Monitor chambers

8. Patient ready for treatment

9. Irradiated GAF Chromic
DETECTORS USED FOR DOSE DISTRIBUTION MEASUREMENTS
DEPTH DOSE DISTRIBUTION
LATERAL DOSE DISTRIBUTION
Markus Ionization chamber
Silicon diode
GAF Chromic Film
Thermoluminescent dosimeters
2 mm
Sensible Volume = 0.05 cm3
Markus Chamber layout
Irradiated GAF Chromic
Risolution 100 m for DDP and 200 m for LDP

10. ‘PURE’ BRAGG PEAK EXPERIMENTAL RESULTS

11. MODULATED BRAGG PEAK

12. EXPERIMENTAL LATERAL DOSE DISTRIBUTION

13. Geant4 applications in prothon therapy our goals
Simulation, design and realization of critical elements of a proton beam line
Scattering system
Modulation system
Collimators along the beam line
Three dimensions dose distribution verification in water at isocenter in the treatment conditions
Comparison with experimental and treatment planning data

14. Proton therapy group in Catania
G. Cuttone Project Leader INFN
G.A.P. Cirrone Qualified Medical Physicist and PhD student
V. Salamone
L. Raffaele
M.G. Sabini
L. Valastro
P. Lojacono
V. Patti
Qualified Medical Physicist
Student for Medical Physics Qualification