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William V. Sharp, M. D. , Steven P. Schmidt, Ph. D. , Duane L

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Presentation on theme: "William V. Sharp, M. D. , Steven P. Schmidt, Ph. D. , Duane L"— Presentation transcript:

1 Prostaglandin biochemistry of seeded endothelial cells on Dacron prostheses 
William V. Sharp, M.D., Steven P. Schmidt, Ph.D., Duane L. Donovan, M.D.  Journal of Vascular Surgery  Volume 3, Issue 2, Pages (February 1986) DOI: / (86) Copyright © 1986 Society for Vascular Surgery and North American Chapter, International Society for Cardiovascular Surgery Terms and Conditions

2 Fig. 2 Patency and thrombus-free surface area of non-endothelial cell-seeded grafts. NM = nonmedicated; A/Di = aspirin (300 mg)/dipyridamole (50 mg twice daily); A/h = high-dose aspirin (300 mg daily); A/l = low-dose aspirin (75 mg every other day); U-5 = U-53,059 (3 mg/kg daily); Ibu =1buprofen (10 mg/kg daily); Dip = dipyridamole (50 mg twice daily); U-6 = U-63557A (10 mg/kg daily); TFS = thrombus-free surface. Journal of Vascular Surgery 1986 3, DOI: ( / (86) ) Copyright © 1986 Society for Vascular Surgery and North American Chapter, International Society for Cardiovascular Surgery Terms and Conditions

3 Fig. 3 Patency and thrombus-free surface area of endothelial cell-seeded grafts. For legend see Fig. 2. Journal of Vascular Surgery 1986 3, DOI: ( / (86) ) Copyright © 1986 Society for Vascular Surgery and North American Chapter, International Society for Cardiovascular Surgery Terms and Conditions

4 Fig. 4 Mean PGI2 production by 4 mm biopsy punches (seeded vs. nonseeded graft). N = nonmedicated; U6 = U-63557A; Ah = high-dose aspirin; Al = low-dose aspirin; AD = aspirin/dipyridamole; D = dipyridamole; Ib = ibuprofen; U5 = U-53,059. Journal of Vascular Surgery 1986 3, DOI: ( / (86) ) Copyright © 1986 Society for Vascular Surgery and North American Chapter, International Society for Cardiovascular Surgery Terms and Conditions

5 Fig. 5 Mean PGI2 production by 4 mm biopsy punches (normal carotid artery). For legend see Fig. 2. Journal of Vascular Surgery 1986 3, DOI: ( / (86) ) Copyright © 1986 Society for Vascular Surgery and North American Chapter, International Society for Cardiovascular Surgery Terms and Conditions

6 Fig. 6 TxB2 production by patent seeded and nonseeded Dacron grafts. For legend see Fig. 2. Journal of Vascular Surgery 1986 3, DOI: ( / (86) ) Copyright © 1986 Society for Vascular Surgery and North American Chapter, International Society for Cardiovascular Surgery Terms and Conditions

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