1. Supplementary Figure S1B

2. Supplementary Figure S2

3. Supplementary Figure S3

4. Supplementary Figure S4

5. Supplementary Figure S5B C D

7. Supplementary Figure S6B
LRP1B relative expression ratio

8. LRP1B Relative Expression*
Supplementary Table S3
Cell Line
LRP1B Relative Expression*
2q21 Copy Number
DNA Methylation %
miR-548a-5p
Expression
8q22.3 Copy Number
Summary of
LRP1B Hits
KAT4 1
94% +2
- Copy number loss
- DNA Methylation (complete)
ARO
8505C
-21603 0% +6 4
- miR overexpression
BCPAP
-16433 2
+15
miR overexpression (high) K1
-2551 3
+35 6
- Copy number gain
- miR overexpression (very high)
TPC-1
-1280 6%
+56 5
NPA
-1241 5%
+22
- miR overexpression (high)
XTC-1
-1117
77%
+11
DNA Methylation (partial)
miR overexpression (moderate)
C643
-233 7%
Copy number loss
HTH74
-156 +5
miR overexpression (low)