1. Regulation of Fluid and Electrolyte Balance Prof. K. Sivapalan

2. Regulation of Fluid and Electrolyte Balance June 20132Regulation of fluid and electrolytes

3. Regulation of Osmolality June 20133Regulation of fluid and electrolytes

4. Renal Excretion of Water and Electrolytes About 180 liters are flitered. About 7/8 reabsorbed in PCT Rest in the other portions of the tubule. About 18 liters of water absorbed in collecting dut under ADH About 180 liters are flitered. About 7/8 reabsorbed in PCT Rest in the other portions of the tubule. About 18 liters of water absorbed in collecting dut under ADH June 20134Regulation of fluid and electrolytes

5. Effects of Drinking Water June 20135 Drinking water dilutes plasma. But due to inhibition of ADH secretion urine flow increases within 30 minutes without increase in solute excretion. In about 2-2.5 hours excess water is eliminated. Reverse occurs in dehydration Regulation of fluid and electrolytes

6. Thirst Mechanism June 20136Regulation of fluid and electrolytes

7. Regulation of Volume June 20137Regulation of fluid and electrolytes

8. Control of Sodium Balance June 20138Regulation of fluid and electrolytes

9. Aldosterone Angeotensin II stimulates secretion of aldosterone from Adrenal Cortex. Aldosterone increases sodium absorption in renal tubules, preventing excretion. June 20139Regulation of fluid and electrolytes

10. Over Hydration- Oedema June 201310Regulation of fluid and electrolytes

11. Causes of Oedema June 201311Regulation of fluid and electrolytes

12. Increased Tissue Fluid June 201312Regulation of fluid and electrolytes

13. Increased capillary pressure June 201313Regulation of fluid and electrolytes

14. Decreased plasma proteins June 201314Regulation of fluid and electrolytes

15. Increased capillary permeability June 201315Regulation of fluid and electrolytes

16. Blockage of lymph return June 201316Regulation of fluid and electrolytes

17. Dehydration June 201317Regulation of fluid and electrolytes

18. Causes of Dehydration June 201318Regulation of fluid and electrolytes