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ECETOC TRA tool Proposed application to estimate PEC/PNEC ratio for substances with risk score = 1 ECETOC has developed a tiered approach for calculating.

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Presentation on theme: "ECETOC TRA tool Proposed application to estimate PEC/PNEC ratio for substances with risk score = 1 ECETOC has developed a tiered approach for calculating."— Presentation transcript:

1 ECETOC TRA tool Proposed application to estimate PEC/PNEC ratio for substances with risk score = 1 ECETOC has developed a tiered approach for calculating the exposure and related risks to consumers, workers and the environment caused by chemicals: Tier 1: based on pre-defined and conservative use scenarios corresponding to Environmental Release Categories (ERC) described under REACH Guidance (Chapter R.16) Tier 2: detailed risk assessment on previously identified uses (additional more realistic exposure input) Developed in Excel, contains the user interface and the datasheets Freely downloadable after registration from:

2 Substance input interface
ECETOC TRA tool Options for retrieval and storage of information from and to the database Substance input interface 2

3 ECETOC TRA tool Input to Environment Assessment
Use scenarios definition Reference values (e.g. PNEC) entry 3

4 ECETOC TRA tool Environment Assessment Output interface
PEC and risk ratio (PEC/PNEC) derivation

5 Example of application
ECETOC TRA tool Example of application Input data Name of the substance = Galaxolide CAS Number = Sector of use (SU) = Private houdeholds (from IUCLID db: personal and domestic use as cosmetics, odour agents and detergents) Molecular weight = 258,40642 mol/g Vapour pressure = 7,27E-02 Pa Water solubility = 4,86E-07 mg/L Partition coefficient octanol-water (log) = 5,86E+00 Biodegradability test result = not biodegradable Life cycle stage = service life ERC = ERC10b, i.e. wide dispersive outdoor use of long-life articles and materials with high or intended release (from IUCLID db: wide dispersive use)

6 Example of application
ECETOC TRA tool Example of application Output data PEC local freshwater = 3,00E-01 mg/L PEC local freshwater sediment = 7,64E+01 mg/Kg(wwt) PEC local marine environment = 2,98E-02 mg/L PEC marine sediment = 7,58E+00 mg/Kg(wwt) PEC in STP = 2,74E+00 mg/L Total daily intake man via the environment local = 9,42E+00 mg/Kg(dw)/d RCR local freshwater = 8.19E+02

7 ERC under REACH

8 ERC under REACH ERC is selected according to the most realistic worst case scenario for the substance of concern


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