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Rapid and accurate detection of rifampin and isoniazid-resistant Mycobacterium tuberculosis using an oligonucleotide array  W.-L. Huang, Z.-J. Hsu, T.C.

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Presentation on theme: "Rapid and accurate detection of rifampin and isoniazid-resistant Mycobacterium tuberculosis using an oligonucleotide array  W.-L. Huang, Z.-J. Hsu, T.C."— Presentation transcript:

1 Rapid and accurate detection of rifampin and isoniazid-resistant Mycobacterium tuberculosis using an oligonucleotide array  W.-L. Huang, Z.-J. Hsu, T.C. Chang, R. Jou  Clinical Microbiology and Infection  Volume 20, Issue 9, Pages O542-O549 (September 2014) DOI: / Copyright © 2013 European Society of Clinical Infectious Diseases Terms and Conditions

2 FIG. 1 Layout of probes on the array (a) position marker, (b) positive control, (c) internal amplification control and (d) wild-type probe. Clinical Microbiology and Infection  , O542-O549DOI: ( / ) Copyright © 2013 European Society of Clinical Infectious Diseases Terms and Conditions

3 FIG. 2 The array and the GenoType MTBDRplus test yielded different results in some cases. Three multidrug-resistant Mycobacterium tuberculosis isolates (a–c) and one isoniazid (INH) mono-resistant isolate (d) were analysed with the array and the GenoType MTBDRplus test, and discrepant results were obtained. RIF, rifampin. Clinical Microbiology and Infection  , O542-O549DOI: ( / ) Copyright © 2013 European Society of Clinical Infectious Diseases Terms and Conditions


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