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Rapid diagnosis of pyrazinamide-resistant multidrug-resistant tuberculosis using a molecular-based diagnostic algorithm  S.O. Simons, T. van der Laan,

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Presentation on theme: "Rapid diagnosis of pyrazinamide-resistant multidrug-resistant tuberculosis using a molecular-based diagnostic algorithm  S.O. Simons, T. van der Laan,"— Presentation transcript:

1 Rapid diagnosis of pyrazinamide-resistant multidrug-resistant tuberculosis using a molecular-based diagnostic algorithm  S.O. Simons, T. van der Laan, A. Mulder, J. van Ingen, L. Rigouts, P.N.R. Dekhuijzen, M.J. Boeree, D. van Soolingen  Clinical Microbiology and Infection  Volume 20, Issue 10, Pages (October 2014) DOI: / Copyright © 2014 European Society of Clinical Infectious Diseases Terms and Conditions

2 FIG. 1 Study Algorithm. FN, false-negative index test result; FP, false-positive index test result; INH, isoniazid; MDR-TB, multidrug-resistant tuberculosis; MGIT, mycobacterial growth indicator tube; PZA, pyrazinamide; Rif, rifampicin; rpoB+ patient, patients with a positive Mycobacterium tuberculosis culture carrying a mutation in the rpoB gene: -r, resistant; -s, susceptible; TN, true-negative index test result; TP, true-positive index test result. Clinical Microbiology and Infection  , DOI: ( / ) Copyright © 2014 European Society of Clinical Infectious Diseases Terms and Conditions


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