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Negative Thyroid Transcription Factor 1 Expression Defines an Unfavorable Subgroup of Lung Adenocarcinomas  Yiliang Zhang, MD, Rui Wang, MD, PhD, Yuan.

Published byManoel Valverde Aranha Modified over 5 years ago

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Presentation on theme: "Negative Thyroid Transcription Factor 1 Expression Defines an Unfavorable Subgroup of Lung Adenocarcinomas  Yiliang Zhang, MD, Rui Wang, MD, PhD, Yuan."— Presentation transcript:

1 Negative Thyroid Transcription Factor 1 Expression Defines an Unfavorable Subgroup of Lung Adenocarcinomas  Yiliang Zhang, MD, Rui Wang, MD, PhD, Yuan Li, MD, Yunjian Pan, MD, Haichuan Hu, MD, Yang Zhang, MD, Hang Li, MD, Lei Shen, MD, Yongfu Yu, MD, Yihua Sun, MD, Haiquan Chen, MD  Journal of Thoracic Oncology  Volume 10, Issue 10, Pages (October 2015) DOI: /JTO Copyright © 2015 International Association for the Study of Lung Cancer Terms and Conditions

2 FIGURE 1 Kaplan-Meier survival curves for recurrence-free survival (RFS) and overall survival (OS) according to TTF1 status. A, RFS in all patients; B, OS in all patients; C, RFS in pathologic stage I patients; D, OS in pathologic stage I patients; E, RFS in the patients with tumors of “pan-negative” mutation; F, OS in the patients with tumors of “pan-negative” mutation. Journal of Thoracic Oncology  , DOI: ( /JTO ) Copyright © 2015 International Association for the Study of Lung Cancer Terms and Conditions

3 FIGURE 2 Kaplan–Meier survival curve for postrecurrence survival.
Journal of Thoracic Oncology  , DOI: ( /JTO ) Copyright © 2015 International Association for the Study of Lung Cancer Terms and Conditions

4 FIGURE 3 There was no significant difference in overall survival (OS; p = 0.749) or postrecurrence survival (PRS; p = 0.505) categorized by different thyroid transcription factor 1 (TTF1) status for those who have received epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI) therapy. Journal of Thoracic Oncology  , DOI: ( /JTO ) Copyright © 2015 International Association for the Study of Lung Cancer Terms and Conditions

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