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Opportunities and Challenges in the Management of Advanced STS

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Presentation on theme: "Opportunities and Challenges in the Management of Advanced STS"— Presentation transcript:

1 Opportunities and Challenges in the Management of Advanced STS

2 Program Goals

3 Sarcoma: The Scope of the Clinical Problem

4 Epidemiology of STS

5 Sarcomas: Biological Groups, Etiology, and Risk Factors

6 Diagnosis and Pathology of Sarcomas

7 Management of Sarcomas: Therapeutic Progress and Ongoing Clinical Needs

8 Doxorubicin vs Intensified Doxorubicin Plus Ifosfamide for Advanced STS: Phase 3

9 Doxorubicin vs Intensified Doxorubicin Plus Ifosfamide: Post-protocol Treatment

10 Pazopanib for Metastatic STS: Phase 3 PALETTE Trial

11 Subanalysis of Phase 2 and 3 Data of Long-term Responders on Pazopanib

12 HRQoL Reported in the PALETTE Study

13 Gemcitabine Plus Docetaxel vs Doxorubicin as First-line Therapy in Metastatic STS: Phase 3 GeDDis Trial

14 GeDDis Trial: Subgroup Analysis

15 Individualizing Therapy for Patients With Advanced STS

16 Abbreviations


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