1. CHOICE study: Relative hazard of ASCVD events by baseline levels of Lp(a), LMW ApoA isoforms, and LMW ApoA isoforms with high Lp(a) vs high-molecular-weight ApoA and low levels of Lp(a)
Measure
Relative hazard p
High Lp(a) concentration (>53 nmol/L vs <53 nmol/L)
1.38
0.02
LMW ApoA isoforms (<22 K-IV repeats vs >22 K-IV repeats)
1.58
<0.0005
LMW ApoA and Lp(a) level >123 nmol/L vs high-molecular-weight ApoA and Lp(a) level <123 nmol/L
1.73
Longenecker JC et al. J Am Soc Nephrol 2005; available at: