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Gene expression profiling diagnosis through DNA molecular computation

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Presentation on theme: "Gene expression profiling diagnosis through DNA molecular computation"— Presentation transcript:

1 Gene expression profiling diagnosis through DNA molecular computation
Allen P. Mills, Jr. TRENDS in Biotechnology, vol 20 No.4 (2002) MEC Seminar Su Dong Kim (C) 2002, SNU Biointelligence Lab, 

2 (C) 2002, SNU Biointelligence Lab, http://bi.snu.ac.kr/
Introduction Gene expression profiling ; (mRNA : cDNA) DNA microarray Adleman DNA self-assembly computer DNA neural network Expression profiling should be feasible using a DNA neural network acting directly on cDNA (C) 2002, SNU Biointelligence Lab, 

3 (C) 2002, SNU Biointelligence Lab, http://bi.snu.ac.kr/
DNA computation Adleman’s in vitro DNA solution of HPP (1994) (C) 2002, SNU Biointelligence Lab, 

4 (C) 2002, SNU Biointelligence Lab, http://bi.snu.ac.kr/
Perceptron (C) 2002, SNU Biointelligence Lab, 

5 (C) 2002, SNU Biointelligence Lab, http://bi.snu.ac.kr/
DNA Neural Networks (1) Steps in forming an axon (C) 2002, SNU Biointelligence Lab, 

6 (C) 2002, SNU Biointelligence Lab, http://bi.snu.ac.kr/
DNA Neural Networks (2) Single layer DNA Neural Network represented by DNA (C) 2002, SNU Biointelligence Lab, 

7 (C) 2002, SNU Biointelligence Lab, http://bi.snu.ac.kr/
Experimental Results (C) 2002, SNU Biointelligence Lab, 

8 Expression Profiling Neural Network
(C) 2002, SNU Biointelligence Lab, 


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