1. The STENT Thrombosis Study
10,000 consecutive patients receiving DES at up to 12 sites
Aspirin and clopidogrel responsiveness evaluated
Using the Accumetrics VerifyNow system
Clinical Follow-Up for 2-5 years
Angiographic core lab assessment of all
stent thromboses and 1:3 matching controls
Supported by grants from Boston Scientific (lead contributor), Accumetrics, Abbott Vascular, Cordis, and Medtronic
Presented at TCT 2006

2. The E-Select Registry and INSIGHT Randomized Trial
30,000 patient global registry + U.S. randomized trial
of standard vs. long duration clopidogrel
Sponsor: Cordis Corp.
The PROTECT Randomized Trial
8,000 patient global randomized trial of the Endeavor vs.
the Cypher stent. Primary Endpoint = stent thrombosis
Sponsor: Medtronic Corp.
Presented at TCT 2006