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Clinical Pearls on the Management of Immune-Mediated Adverse Events Affecting the Genitourinary Tract.

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Presentation on theme: "Clinical Pearls on the Management of Immune-Mediated Adverse Events Affecting the Genitourinary Tract."— Presentation transcript:

1 Clinical Pearls on the Management of Immune-Mediated Adverse Events Affecting the Genitourinary Tract

2 Introduction

3 Possible Mechanisms

4 Organ Systems Affected by Immune Checkpoint Blockade

5 General Principles of Management

6 The Team Approach

7 Educating the Front Lines

8 Specialists

9 GU-Mediated AEs

10 Role of Kidney Function

11 Cisplatin-Ineligible Patients With Bladder Cancer

12 PD-1/PD-L1 Blockade in Cisplatin-Ineligible Patients With Bladder Cancer

13 Case 1

14 Approaches Prior to Instituting Systemic Therapy

15 Case 1 (cont)

16 Monitoring

17 Imaging

18 Case 1 (cont)

19 Concerns

20 Case 1 Conclusion

21 Case 2

22 Concerns

23 Case 2 (cont)

24 Multidisciplinary Care

25 Nephritis

26 Management of Nephritis

27 Case 2 Conclusion

28 Concluding Remarks

29 Abbreviations


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