1. Mitigating the Challenge of Immune-Related AEs in the Emergency Department

2. Introduction to Checkpoint Inhibitors

3. MOA of PD-1/PD-L1 Pathway

4. FDA-Approved Checkpoint Inhibitors

5. Checkpoint Inhibitors in Oncology

6. The Breadth of irAEs

7. Immune-Related AEs in the ED

8. Patient Evaluation for irAEs in the ED

9. Management of irAEs in the ED

10. Challenges of irAEs in the ED

11. Case 1: 42-Year-Old Woman With Advanced Melanoma

12. Case 1: Management of Colitis

13. Case 2: 68-Year-Old Man With Advanced Lung Cancer

14. Variety of Pneumonitis Presentations

15. Case 2: Management of Pneumonitis

16. Case 3: 57-Year-Old Woman With Renal Cell Carcinoma

17. Case 3: Management of Hypophysitis

18. Additional irAEs to Consider

19. Additional irAEs to Consider (cont)

20. Additional irAEs to Consider (cont)

21. Summary

22. Abbreviations

23. Abbreviations (cont)