1. ? Glucose uptake, Storage, Lipogenesis
WHY?
16.08.jpg
Glucose uptake, Storage, Lipogenesis
The Integrator integrates multiple inputs

2. Another hormone that regulates plasma glucose concentration
Glucagon prevails during post-absorptive phase
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Transition from absorptive to post-absorptive phase?

3. Fig
EPI, yet another horomone in glucose homeostasis
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4. Glucose-counterregulatory controls (oppose effects of insulin)
Glucagon
Epinephrine
Cortisol (permissive effect)
Growth hormone (permissive effect)

5. Who Cares?

6. A Case Study On our website at

7. Oral Glucose Tolerance Test
Overnight fast, no beverages other than water
Fasting blood sample
Ingest 75 grams glucose
Blood samples every 0.5 hours for 3-5 hours
Plot plasma glucose concentration over time
Compare curves

8. Hypoglycemia 60

9. Stress, Emergency (fight or flight)
Effect on Alpha Cells
Effect on
Beta cells

10. The Answer to the Problem?
Rationale for substituting protein for carbohydrate midnight snack?

11. Acid Reflux (-) Proteins & amino acids in stomach (-)
Enteroendocrine cells of stomach
Gastrin
HCl secretion by Parietal cells in
stomach
Hydrolysis of proteins