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The immune metagene model has prognostic value in IBE but not in IBD breast cancer. The immune metagene model has prognostic value in IBE but not in IBD.

Published byElisabeth Manning Modified over 5 years ago

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Presentation on theme: "The immune metagene model has prognostic value in IBE but not in IBD breast cancer. The immune metagene model has prognostic value in IBE but not in IBD."— Presentation transcript:

1 The immune metagene model has prognostic value in IBE but not in IBD breast cancer.
The immune metagene model has prognostic value in IBE but not in IBD breast cancer. A, heatmap of metagene gene expression levels (rows) across 1,954 tumors (columns) as described in ref. 12. Key shows color scale of mean centered, log2-transformed gene signal intensities. For each metagene, tumors are sorted left to right by ascending metagene scores; tertile thresholds are shown (33rd and 66th percentiles) for defining low (L), intermediate (I), and high (H) tertiles. B, IMM prognostic risk groups are shown. C and D, IBE and IBD type tumors are stratified by IMM subclasses (FID, WID, and PID) in Kaplan–Meier plots of DMFS. The number of tumors (n) in each subclass is shown; the log-rank P value is reported. Lance D. Miller et al. Cancer Immunol Res 2016;4: ©2016 by American Association for Cancer Research

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A B C Supplementary Figure S1. Time-dependent assessment of grade, GGI and PAM50 in untreated patients Landmark analyses of the Kaplan-Meier estimates.

A B C Supplementary Figure S1. Time-dependent assessment of grade, GGI and PAM50 in untreated patients Landmark analyses of the Kaplan-Meier estimates.
Date of download: 5/29/2016 Copyright © 2016 American Medical Association. All rights reserved. From: Gene Expression Signatures, Clinicopathological Features,

Date of download: 5/29/2016 Copyright © 2016 American Medical Association. All rights reserved. From: Gene Expression Signatures, Clinicopathological Features,
Homozygous deletions within chromosome 9q23.

Homozygous deletions within chromosome 9q23.
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Fig. 8. Recurrent copy number amplification of BRD4 gene was observed across common cancers. Recurrent copy number amplification of BRD4 gene was observed.
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