1. Foetal surgery and cleft lip and palate: current status and new perspectives 
N.A. Papadopulos, M.A. Papadopoulos, L. Kovacs, H.F. Zeilhofer, J. Henke, P. Boettcher, E. Biemer 
British Journal of Plastic Surgery 
Volume 58, Issue 5, Pages (July 2005)
DOI: /j.bjps
Copyright © 2005 The British Association of Plastic Surgeons Terms and Conditions

2. Figure 1
A foetus at a GA of 144 days with the repaired cleft lip (indicated by the arrow). Note the slight asymmetry of the upper lip with some notching at the wound closure line: in this foetus for the repair of the alveolar defect an iliac crest graft has been used. Reproduced with the permission of Journal of Cranio-Maxillofacial Surgery: Papadopulos NA, et al. Intrauterine autogenous fetal bone transplantation for the repair of cleft-like defects in the midgestational sheep model. J Cranio-Maxillofac Surg 2004;32(4):199–210.
British Journal of Plastic Surgery  , DOI: ( /j.bjps )
Copyright © 2005 The British Association of Plastic Surgeons Terms and Conditions

3. Figure 2
(A) 3D-CT and (B) 2D-MPI of a foetus at a GA of 144 days demonstrating healed maxillary alveolar defect (ulnar bone graft and GoreTex® titanium-reinforced membrane have been used for the repair of the alveolar defect). Note the lack of callus formation at the repaired side and the radiopacity of the titanium reinforced membrane (left). (A′) 3D-CT and (B′) 2D-MPI of the negative control group. (A″) 3D-CT and (B″) 2D-MIP of a foetus at a GA of 145 days (iliac crest bone graft has been used for the repair). The maxillary defect has not healed and the maxilla is deviated toward the nonoperated side (right side). Reproduced with the permission of Journal of Cranio-Maxillofacial Surgery: Papadopulos NA, et al. Intrauterine autogenous fetal bone transplantation for the repair of cleft-like defects in the midgestational sheep model. J Cranio-Maxillofac Surg 2004;32(4):199–210.
British Journal of Plastic Surgery  , DOI: ( /j.bjps )
Copyright © 2005 The British Association of Plastic Surgeons Terms and Conditions

4. Figure 3
H&E maxillary bone skeleton stain at 1.5× original magnification. A foetus at a GA of 140 days with histological evidence of healing of the alveolar defect after ulnar graft transplantation. The upper arrow indicates the repaired cleft lip side and the lower arrow the healed maxillary alveolar defect. Note the lack of maxillary continuity at the nonoperated side on the left (false-positive). Reproduced with the permission of Journal of Cranio-Maxillofacial Surgery: Papadopulos NA, et al. Intrauterine autogenous fetal bone transplantation for the repair of cleft-like defects in the midgestational sheep model. J Cranio-Maxillofac Surg 2004;32(4):199–210.
British Journal of Plastic Surgery  , DOI: ( /j.bjps )
Copyright © 2005 The British Association of Plastic Surgeons Terms and Conditions