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Podocyte-specific PPAR-γ–deficient mice show increased glomerular TRPC6 expression. Podocyte-specific PPAR-γ–deficient mice show increased glomerular TRPC6.

Published byWidya Darmadi Modified over 5 years ago

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Presentation on theme: "Podocyte-specific PPAR-γ–deficient mice show increased glomerular TRPC6 expression. Podocyte-specific PPAR-γ–deficient mice show increased glomerular TRPC6."— Presentation transcript:

1 Podocyte-specific PPAR-γ–deficient mice show increased glomerular TRPC6 expression.
Podocyte-specific PPAR-γ–deficient mice show increased glomerular TRPC6 expression. Glomerular TRPC6 (A) protein and (B) mRNA expression was determined. In addition, protein expression of (C) desmin and (D) nephrin was measured in podocyte–specific PPAR-γ–deficient (KO) mice as well as their wild-type littermates. Protein expression is depicted relative to the mean expression in wild-type mice; n=4 animals per group. Statistical significance was determined using an unpaired t test. Ctr, control. *P<0.05 versus wild-type littermates. Ramon Sonneveld et al. JASN 2017;28: ©2017 by American Society of Nephrology

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