1. Evaluation of models incorporating the base covariates.
Evaluation of models incorporating the base covariates. (A) AUCs and 95% confidence intervals are illustrated for the ROC curves derived from the models incorporating the base covariates delta VEH, delta TNF, EC50 VEH, EC50 TNF, EC10 VEH, EC10 TNF, R10 VEH, or R10 TNF. The covariates are listed on the left, and the AUC for each is shown on the right next to the 95% confidence interval (shown in brackets). *P < 0.05 (statistically significant difference between ROC curves as determined by DeLong’s test) (DeLong et al., 1988). (B) ROC curves were generated and indicate for each model the 95% confidence interval shaded in gray. The covariates incorporated in the model are listed on the bottom right corner of each ROC curve.
Ashley R. Maiuri et al. J Pharmacol Exp Ther 2017;362:
Copyright © 2017 by The American Society for Pharmacology and Experimental Therapeutics