1. Complex Patterns of Inheritance
Section 10.3 & Chapter 11

2. Exceptions to Mendelian Genetics
Summary
Exceptions to Mendelian Genetics
Polygenic
Incomplete Dominance
Co-Dominance
Multiple Alleles
Pleiotropy
Gene linkage
Sex-linked Traits
OTHER Extension:
Karyotype
Pedigrees
Patterns of inheritance
Inferring genotype
Non-disjunction - trisomy

4. Where is this happening again?

5. Complete Dominance

8. Different?

15. Multiple Alleles

16. glycoproteins = antigens
A B – Codominance / multiple alleles
I or i = do not make A or B
A, B > i dominance
A=B  Codominant
Rh Factor = + or - ….another glycoprotein – present or absent
Genotypes (6) = Phenotypes (4)
AA, Ai = A
BB Bi = B
AB = AB
ii = O

17. Universal receptor (+)
Universal donor ( O -)

18. Poly-genic Traits

19. Pleiotropy occurs when one gene influences two or more seemingly unrelated phenotypic traits. Consequently, a mutation in a pleiotropicgene may have an effect on some or all traits simultaneously. Anexample is phenylketonuria, a human disease that affects multiple systems but is caused by one gene defect.
Pleiotropy: Cystic fibrosis is a good of example of pleiotropy, where a mutation in a single gene affects multiple systems in this case the lungs, pancreas, and sweat glands

20. Compare and Contrast

21. Exceptions to Mendelian Genetics
Summary
Exceptions to Mendelian Genetics
Polygenic
Incomplete Dominance
Co-Dominance
Multiple Alleles
Pleiotropy
Gene linkage
Sex-linked Traits
OTHER Extension:
Karyotype
Pedigrees
Patterns of inheritance
Inferring genotype
Non-disjunction - trisomy

23. BIO SmartStarter – 11/20/15 Xb - Color Blind XB – not Color Blind
1. Make a Punnett square for the cross illustrated here.
2. What are the genotypic and phenotypic ratios (probabilities) for the offspring?