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CALCIUM PYROPHOSPHATE DIHYDRATE (CPPD) CRYSTAL DEPOSITION DISEASE

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Presentation on theme: "CALCIUM PYROPHOSPHATE DIHYDRATE (CPPD) CRYSTAL DEPOSITION DISEASE"— Presentation transcript:

1 CALCIUM PYROPHOSPHATE DIHYDRATE (CPPD) CRYSTAL DEPOSITION DISEASE
Pseudogout

2 Red, hot inflammed joint. Not uncommon in shoulder, or hip
Red, hot inflammed joint. Not uncommon in shoulder, or hip. Poly articular fasion, mimic RA Lose joint sense Calcium crystal deposited in cartilage (major difference from gout, in bone and around soft tissues) May be asymptomatic except ca in cartilage Seen many in hospitalized pt p surgery

3 CPPD CRYSTAL DEPOSITION DISEASE: DISEASE ASSOCIATIONS
Hyperparathyroidism Hemachromatosis – iron overload Osteoarthritis Hypomagnesemia Familial Hypophosphatasia Vast majority have osteoarth.

4 Osteoarthritic joints DIP
Ca deposit in wrist. In cartilage

5

6 Ca deposit in mesisci of knee

7 Articular cart/linear deposit along head of humerous

8 Bony fragmentation of ankle joint

9 Dx seen with crystals under microscope
Dx seen with crystals under microscope. Arrangement opposite of gout crystals

10 TREATMENT OF PSEUDOGOUT
NSAIDS Intra-articular steroids PO colchicine prophylaxis Can quiet down acute episodes but no good way to limit recurrent attacks


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