1. Exercise 10
Muscle histology

2. Muscle Types
Skeletal – attached to bone by tendons is responsible for voluntary movements.
Cardiac- located in heart
Smooth- located in the walls of internal organs, blood vessels, and airways

3. Skeletal muscle fibers
Connective tissue layers:
Epimysium- around the entire muscle
Perimysium surrounds bundle of muscle fibers (fascicle)
Endomysium- surrounds each muscle fiber

4. Skeletal muscle cont.
Striations in appear because of alternating light and dark bands from the arrangement of the thick and thin protein filaments called myofibrils.

5. Skeletal muscle

6. Cardiac muscle Forms branching networks. Striated
Linked together by intercalated discs

7. Smooth Muscle Widest in middle and tapered toward each end.
Single nucleus

8. Cell structure of skeletal muscle
Actin- main component of thin filaments.
Myosin- main component of thick filaments
Together these are called myofilaments which are packaged into parallel bundles called myofibrils.

9. Structure of a skeletal muscle fiber

10. Structure of a skeletal muscle fiber
Sarcolemma or cell membrane
T-tubules- continuous with the sarcolemma and travel into the cytoplasm
Sarcoplasmic reticulum-SER
Cisternae- saclike extensions of the SR

11. Neuromuscular Junctions
Synaptic terminal- the expanded knob at the end of the nerve fiber
Motor end plate-the region of the sarcolemma associated with the neuromuscular junctions.
Synaptic cleft- narrow space between the cell membrane

12. The End View the different types of muscle under the microscope.
Be able to ID the various terms on models, pictures or on slides