1. 2002–2006 Mid and Other sized companies continued to launch the majority of NMEs
APRIL 2007
SOURCE: CMR INTERNATIONAL PERFORMANCE METRICS PROGRAM © THOMSON REUTERS Your use of these materials is subject to the terms and conditions hereof. Please read the disclaimer carefully before using these materials.

2. Profile of New Launches
Chapter 2
2002–2006 Mid and Other sized companies continued to launch the majority of NMEs
Profile of New Launches
Figure 2.2
Key message
In 2006, Major companies accounted for 44% of new molecular entities first launched globally, having shown a steady improvement since 2004, when major companies accounted for only 25% of new molecular entities launched.
Methodology
Annual surveys of the global pharmaceutical industry have been undertaken to identify all NMEs introduced for the first time anywhere in the world. The number of each year’s output that was first marketed (although not necessarily discovered) by Major companies is presented. Note that the activities of companies that now form part of a larger company, due to merger and acquisition activities, have been attributed to the company group as it existed in 2006.
Key Definitions
New Molecular Entity (NME): A new chemical entity or biological (including products of biotechnology) that has not been previously available for therapeutic use in man and are destined to be made available as a ‘prescription only medicine’, to be used for the cure, alleviation, treatment, prevention or in vivo diagnosis of diseases in man. Vaccines, new salts, pro drugs, metabolites and esters of existing compounds and certain biological compounds (e.g. antigens) are not classified as NMEs. Combination products are excluded from the list unless one or more of the constituents of the combination product has never been previously available.
CMR International Performance Metrics Programme / Source
Annual Survey of New Molecular Entity First Launches / New Medicine Launches A complete guide to New Molecular Entities (NMEs) launched world-wide.
NME launches by Major companies have been included in this analysis even where the launch was made jointly with a Mid or Other company
Major companies are defined as those spending ≥US$ 1.8 billion in 2006 on ethical pharmaceutical R&D.
SOURCE: CMR INTERNATIONAL PERFORMANCE METRICS PROGRAM © THOMSON REUTERS

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