1. Heart Pump and Circulatory System

2. Agenda Review of Team Action Items Laboratory Layout and Cleanup
System Response Observations
LabVIEW Development
Machining Plans
Electrical System
Updated BOM
Test Plans
Risk Assessment
Plans for MSD II

3. Review of Team Action Items
Group:
Generate detailed test plans
Update BOM
Develop detailed plans for MSD 2
Develop list and answer questions for team progress report
Update Risk Assessment
Kevan:
Ensure plate is received (and check quality, etc)
Create machining plan and timeline for parts
Machine parts
Assist ventricle fabrication and testing
Susan:
Edit Edge from review comments
Work with Mike during team meeting to develop LabVIEW program and test sensors for accuracy
Force and material analysis for the Ventricle
Write up team progress report
Mike:
Develop test protocols for sensors and test using labview
Work with Blake to develop new compliance tank design as backup
Finish simulink analysis
Work with Susan to begin layout of control system
Blake:
Finalize simulink modeling; look over with Dr. Rice
Find flow outputs along loop using flow meter and pressure sensors
Verify sealing components throughout model (ex. O-rings, Compliance tank caps)
Additional analysis to compliance tanks
Henry:
Fabricate the ventricle
Test the ventricle
Assist in machining of new parts
Assist in the implementation of the driver to our ventricle pump

4. Progress Report

5. Proposed Pressure Sensor Location

6. Proposed Laboratory Layout

7. Laboratory Maintenance
Weekly Procedure: (Post-Experimentation)
Drain distilled water from system
Siphon out water by priming hose from aortic compliance tank to nalgene container
Force out systems water via vacuum pressure
Semi-Annual Procedure:
Add 10 grams of Alconox to 1 liter of distilled water & mix
Pour solution into aortic tank of system
Initiate system for operation
Run system for approximately 10 minutes until tubing cloudiness becomes clear
Drain solution
Disassemble ventricle pump, valves, tanks, sensors
Rinse interior of all components
Store components in lab storage room

8. System Response Observations
Motivation: Analyze the total latency of air driver.
Methods: Use Oscilloscope to measure delay from Computer Signal to Solenoid trigger. Compare various speeds(1Hz, 1.5Hz, 2Hz, 2.5Hz)
Analysis: Results found no statistically relevant variability in latency at various speeds with an average of ~59ms.
Conclusion: Latency will be evaluated for relevance during system testing and used to tune code.

9. Calibration Flowchart

10. LabVIEW Programs (Flowmeter)

11. LabVIEW Programs (Relay)

12. Prototyping Progress
The mold turned out very well. The air bubbles were minimal and largely restricted to the flange; where it will least affect the structural integrity of the ventricle. These air bubbles could have been avoided, but I poured the mix a little too fast and may have been clamped down a bit quick. Some of the surfaces are a bit uneven as well. This can be solved with some extra sanding of some of the harder to reach places. The ventricle compresses much easier than expected, while still appearing to be very durable. Overall, these are very successful results

13. Future Prototyping
Goal: Create several ventricle prototypes that can simulate physiological conditions based on wall thickness and compare to theoretical values predicted using finite element analysis.
Plan: Mold additional ventricle prototypes with Dragon Skin silicone (of varying thicknesses) and compare to current prototype performance.
Outcome: Ventricle chosen best models desired physiological conditions of a human heart.

14. Machining Plans
The drawings have been refined to their current state as shown here. We consulted with SME Rob Kranick who had some ideas, especially for sealing the chamber. However this was before the revelation that the ventricle will require considerably less pressure to compress. We can combine this with how smoothly the rough assembly went to make the call that we will not need the design change we had originally intended for dealing with the seal

15. Current Status -12’’x12’’x1/2’’ cut down to size
-Currently 5.7’’x5.7’’x1/2’’ plates

16. Future Machining
In order to maintain a proper seal in the chamber, the slots for the acrylic tubes need to be as concentric as possible - all other drilled holes are based on their dimension. The next phase of the process will be to machine the tube slots and ensure a proper fit before drilling the through holes used to secure the chamber in place to ensure accuracy. The ventricle hole, however, will need to be re-drawn in order for the machine shop to accurately advise us on how to machine it (radius of arc instead of ellipse).

17. Electrical Schematic
DAQ
Regulator amp
Relays
New Additions Circled

18. Air Driver Prototype
Reduced risk with emergency stop button and circuit breaker
Internal solenoid for noise reduction
Currently using box donated by the construct

19. Updated BOM

20. Test Plans Solenoid Testing (S1) Compliance Testing (S2, S3, and S4)
Ventricle Pressure Testing (S5, S6, and S20)
Life Cycle Testing (S7)
Maintenance Testing (S8)
Flowmeter Testing (S9)
Equilibrium Testing (S11 and S15)
Air Safety Testing (S14)
Electronic Safety Testing (S16)
Pressure Input Regulation Testing (S17)
Ease of Use Testing (S10, S12, S13, and S18)
Cost Testing (S21)

21. Flowmeter Testing

22. Pressure Input Regulation Testing

23. Lab Cleanup Testing Plans
Bacterial film (biofilm) buildup testing
Leave a small amount of moisture remaining in the system
Allow for system to sit without running for multiple days/weeks
Record Observations per day
Room Temperature
Amount of moisture in the system
Odors from within the system
Visual cloudiness on inner walls of tubing and tanks
Swab cloudy region of inner walls of tubing
Culture bacterial film
Determine additive to avoid or eliminate biofilm during storage

24. Updated Risk Assessment

25. Plans for MSD 2

26. Plans for MSD 2 Continued

27. Plans for MSD 2 Continued

28. QUESTIONS?