1. p16 INK4a andp15 INK4b gene methylations in plasma cells from monoclonal gammopathy of undetermined significance
by Gaëlle Guillerm, Emmanuel Gyan, Darius Wolowiec, Thierry Facon, Hervé Avet-Loiseau, Kazimierz Kuliczkowski, Francis Bauters, Pierre Fenaux, and Bruno Quesnel
Blood
Volume 98(1):
July 1, 2001
©2001 by American Society of Hematology

2. Methylation-specific PCR of thep15INK4b and p16INK4a genes in selected plasma cells from patients with MGUS.MS-PCR was performed with specific primers for unmethylated (U) and methylated (M) p15INK4b and p16INK4a alleles in Raji and RPMI-8226 cell lines as ...
Methylation-specific PCR of thep15INK4b and p16INK4a genes in selected plasma cells from patients with MGUS.MS-PCR was performed with specific primers for unmethylated (U) and methylated (M) p15INK4b and p16INK4a alleles in Raji and RPMI-8226 cell lines as control and in CD138-selected MGUS plasma cells (samples 76, 77, 78, and 79). PCR product of appropriate molecular weight indicates the presence of unmethylated and/or methylated (A) p15INK4b (162 bp and 154 bp for U and M, respectively) and (B) p16INK4a alleles (154 bp and 145 bp for U and M, respectively) in that sample.
Gaëlle Guillerm et al. Blood 2001;98:
©2001 by American Society of Hematology