1. Paraneoplastic glomerulopathies: New insights into an old entity
Pierre M. Ronco 
Kidney International 
Volume 56, Issue 1, Pages (July 1999)
DOI: /j x
Copyright © 1999 International Society of Nephrology Terms and Conditions

2. Figure 1
Patient 1. (A) Light microscopy. Note discrete thickening of the glomerular capillary walls and mild podocyte hypertrophy (Masson trichrome; original magnification × 312). (B) Immunofluorescence with anti-γ antibody. Note typical subepithelial deposits (original magnification × 312).
Kidney International  , DOI: ( /j x)
Copyright © 1999 International Society of Nephrology Terms and Conditions

3. Figure 2
Patient 2. (A) Light microscopy. Atypical membranous glomerulonephritis: in addition to the irregular aspect of the capillary walls, note segmental mesangial hypertrophy and cellular proliferation (silver stain; original magnification × 312). (B, C) Immunofluorescence microscopy. Diffuse granular deposits along the capillary walls with predominant subepithelial location. Staining was exclusive for IgG (B) and kappa light chain (C, next page). Original magnification × 312. (D) Electron micrograph of a glomerular capillary. Note subepithelial deposits of fibrillar material cut at various angles. Uranyl acetate and lead citrate (original magnification × 12,000. Reproduced from46).
Kidney International  , DOI: ( /j x)
Copyright © 1999 International Society of Nephrology Terms and Conditions

4. Figure 3
Patient 3. (A) Light microscopy. Nodular glomerulosclerosis. Note moderate mesangial hypercellularity, scarce double-contour aspects, and normal appearance of most tubular basement membranes. PAS stain (original magnification × 312). (B) Electron micrograph of a glomerular capillary. Note diffuse, finely granular, electron-dense deposits along the glomerular basement membrane with effacement of epithelial cell foot processes (uranyl acetate and lead citrate; original magnification × 12,000).
Kidney International  , DOI: ( /j x)
Copyright © 1999 International Society of Nephrology Terms and Conditions

5. Figure 4
Patient 3. Epitope analysis of γ-chain deposits by indirect immunofluorescence. Monoclonal antibodies specific for γ-chain constant domains and for γ1 heavy-chain were used. Deposits reacted with NL16, a monoclonal antibody specific for the γ1 subclass. Note staining of the deposits with anti-CH2 and anti-CH3 antibodies but not with the anti-CH1 antibody (original magnification × 312).
Kidney International  , DOI: ( /j x)
Copyright © 1999 International Society of Nephrology Terms and Conditions