Presentation is loading. Please wait.

Presentation is loading. Please wait.

Overview of Clinical and Translational CHOP

Published byChristiana Payne Modified over 6 years ago

Similar presentations

Presentation on theme: "Overview of Clinical and Translational CHOP"— Presentation transcript:

1 Overview of Clinical and Translational Research @ CHOP
Andrea Kelly, MD, MSCE Associate Director Center for Human Phenomic Science September 2018 Clinical and Translational Research 101

2 Scientific Themes to Prioritize

3 Office of Tech Transfer
Research Institute Leadership Bryan Wolf, MD, PhD Chief Scientific Officer Executive Vice President Richard Aplenc, MD, PhD, MSCE Chief Clinical Research Officer Bev Davidson, PhD Chief Scientific Strategy Officer Fundamental Sciences Matthew Hodgson Assistant Vice President Research Compliance Zev Sunleaf Vice President Office of Tech Transfer Michelle Lewis Vice President of Research Operations

4

5 CHOP Research Institute Campus
Clinical research- most housed at 3535 Market street Basic research- Housed at the Leonard and Madlyn Abramson Pediatric Research Center (many core facilities are also located here), first opened in 1995, and in the Colket Translational Research Building (office and research space), which was opened in 2009 Schulykilll Avenue Building- coming in clinical research to relocate here

6 Research Staffing Prosper—educational programs & training Clinical Trial Support Contracting Recruitment enhancement IND/IDE support Contact: Michele Toms P

7

8 CHOP Center for Human Phenomic Science (CHPS)
Funded by the NIH National Center for Advancing Translational Sciences (NCATS) Supported by the CHOP Research Institute Continuously funded as GCRC then CTSA since early 1960s Mission: to provide the resources, environment, operations, and training to support and promote high-quality clinical and translational research by qualified investigators.

9 CHOP CHPS Cores Nursing (Audrey Kamrin) Sleep Ophthalmology
Outpatient, Inpatient, scatterbed Sample Collection, processing, shipping Vitals Nursing (Audrey Kamrin) Wood Building 4 & 3550 Market St. satellite Polysomnogram Sleep 1 Main Ophthalmology Behavioral Neuroscience (Jerilynn Radcliff) Anthropometrics DXA Peripheral quantitative CT Muscle strength Nutrition (Babette Zemel) 7 Main & 3550 Market St. satellite Database Development (e.g., REDCap) Case Report Forms Informatics Core (Emma Escobar) Study Design Sample Size and Power Calculations Statistical Analysis Biostatistics Core (Justine Shults) ECG Echocardiogram Pulse wave velocity 24-hr ambulatory blood pressure Endopat Cardiovascular (Meryl Cohen) 3 Main Translational Core Lab (Research Institute, Sean Ren) Penn CHPS Lorraine Katz, MD—Director John Krall Sharon Carbonara Call Ext or Website: Junior Investigator Pilot Program Career Development Awards

10

11 Biostatistics and Data Management Core
Study Design Sample Size and Power Calculations Randomization Statistical Analysis Data and Safety Monitoring Boards Grant Applications and IRB Submissions Abstracts and Manuscripts Methodological Research Statistical Consulting Biostatistics Services Database Development and Maintenance (e.g., REDCap) Web-based Systems Case Report Forms Data Entry and Imaging Audits Creation of Analytic Datasets Regulatory Requirements (e.g., FDA, Part 11) Data Management Services The BDMC is located on the CHOP campus at: Roberts Building, 9th Floor

12 Additional Data Analytics Resources
Faculty Biostatistics Group Abbas Jawad, PhD Justine Shults, PhD- Rui Xiao, PhD Healthcare Analytics Unit Heather Griffis, PhD-

13 Research information services (RIS)
Web page for requests

14 CHOP Office of Faculty Development
One-on-one meetings to welcome new CHOP faculty Provide names and describe roles of people who can help with academic career aside from your assigned Mentor and your Chair/Chief Outline departmental specific Faculty Development programs Website management Samples of successful CHOP grants (K-, R-, P- and U-type funding) and templated language for Resources Guidance on setting up a lab or clinical research group Internal (CHOP/Penn) and external (AAMC, Harvard) professional development sessions Faculty development sessions with internal and external speakers Mary Blitzer Field Assistant Director

15

16 Grant Review Groups Pediatrics K and R Advisory Committees
Review of basic and clinical proposals for K and R applications to NIH Neuroscience Grants Club Reviews Rs, Ks, Fs, and private foundation grants; clinical and basic research in neuroscience Attendees include senior faculty, junior faculty, fellows, and post-doctoral fellows Cell Pathology Grants Club Reviews basic research grants at concept stage Attendees include senior and junior faculty from Pathology Grant Proposal Success Groups (Self- Assembled: Current Group focused on Immunology for NIH, foundation and internal grants for early stage investigators or basic science K awards) Learning and networking opportunity for investigators across campus Attendees include senior faculty

17 Office of Postdoctoral Affairs
Provide opportunities for research trainees to participate in career and professional development programming Consider the Diversity Fellowship for postdocs Support trainees in pursuing external funding Visit the CHOP Trainee Portal to find out more about our services and programs Wendy Reed Williams, PhD Director

18 Responsible Research Training
Deliver training programs and events that improve compliance with federal regulations Use the Training Wizard to determine training requirements or contact us, or Wendy Reed Williams, PhD Director

19 Office of Postdoctoral Office of Responsible Research
Affairs Office of Responsible Research Training ACADEMIC PROGRAMMING TRAINING AND ADMINISTRATION Specialized Administrative Support for Postdocs Stipend/Experience Review Career/Professional Dev’t Programs Administration of Research Trainee Advisory Committee Trainee Diversity Programmatic Support Research Training/ Event Coordination Required Research Training Responsible Conduct of Research Instructional Design/ Module Development Poster Day Scientific Symposium Other Events Postdoc/ Physician Fellowship Outreach and Career Development Career Discussions Individual Development Plans Diversity Outreach and Support SACNAS ABRCMS Internship Program Administration CRISSP Science Leadership Academy (SLA) Community College of Philadelphia (CCP) Informal Internships Emerging Partnerships Science Carnival Graduate Undergrad High School

20 Scientific Communities at CHOP Centers of Emphasis
Applied Genomics Cellular and Molecular Therapeutics Childhood Cancer Research Mitochondrial and Epigenomic Medicine Autism Research Injury Research & Prevention Pediatric Clinical Effectiveness PolicyLab Microbiome DBHI Biomedical & Health Informatics Centers target efforts and resources to areas of research that will have the greatest impact on translating basic research findings into medical innovations, part of our bench-to-bedside philosophy.

21 Scientific Communities at CHOP Research Affinity Groups (RAGs)
Professional Society of Clinical Research Clinical Trials Research DNA-Protein Interaction Fetal Biology and Therapy Genes, Genomics and Pediatric Disease Global Health Research Health and Behavior METAChop (Math, Engineering and Technology) Metabolism, Nutrition, and Physical Development Mitochondria mHealth Research Neuroscience Normal and Malignant Hematopoiesis Proteins Protective Immunity and Immunopathology Qualitative Research Methods Research Affinity Groups increase collaboration across disciplines and link CHOP Research investigators who have common research interests.

22

Download ppt "Overview of Clinical and Translational CHOP"

Similar presentations

Mentors and Mentees: Resources for Investigators at MUSC Marc I. Chimowitz, MB,ChB Professor of Neurology Associate Dean of Faculty Development MUSC.

Mentors and Mentees: Resources for Investigators at MUSC Marc I. Chimowitz, MB,ChB Professor of Neurology Associate Dean of Faculty Development MUSC.
Disclosure I, Peter T. Katzmarzyk, PhD, FACSM, have no relationships with commercial interests to disclose. A commercial interest is any entity producing,

Disclosure I, Peter T. Katzmarzyk, PhD, FACSM, have no relationships with commercial interests to disclose. A commercial interest is any entity producing,
Overview of Mentored K Awards Shawna V. Hudson, PhD Assistant Professor of Family Medicine and Community Health UMDNJ-RWJMS The Cancer Institute of New.

Overview of Mentored K Awards Shawna V. Hudson, PhD Assistant Professor of Family Medicine and Community Health UMDNJ-RWJMS The Cancer Institute of New.
July 15, 201010:00 – 11:00 Introduction to Clinical Research: Research Funding and Career Development Michael B. Amey Associate Dean Office of Research.

July 15, :00 – 11:00 Introduction to Clinical Research: Research Funding and Career Development Michael B. Amey Associate Dean Office of Research.
Introduction to Grants Resources in the Health Sciences by Min-Lin Fang, MLIS Education and Information Consultant for Nursing and Social & Behavioral.

Introduction to Grants Resources in the Health Sciences by Min-Lin Fang, MLIS Education and Information Consultant for Nursing and Social & Behavioral.
Grant Review & Analysis Office Heather Offhaus, Director 11/1/2011.

Grant Review & Analysis Office Heather Offhaus, Director 11/1/2011.
Harvard Catalyst: How Can It Help Your Research? Steven D. Freedman MD PhD Professor of Medicine, HMS Associate Dean for Clinical and Translational Research,

Harvard Catalyst: How Can It Help Your Research? Steven D. Freedman MD PhD Professor of Medicine, HMS Associate Dean for Clinical and Translational Research,
Clinical and Translational Science Award (CTSA) John F. Ennever Medical Director, CTO Director, RKSR.

Clinical and Translational Science Award (CTSA) John F. Ennever Medical Director, CTO Director, RKSR.
The Office of Research, Health Sciences

The Office of Research, Health Sciences
Clinical Research Center at a Glance Lynda Lane MS Administrative Director.

Clinical Research Center at a Glance Lynda Lane MS Administrative Director.
Signature Research and Academic Collaborations Status Report to RHEDC February 15, 2007.

Signature Research and Academic Collaborations Status Report to RHEDC February 15, 2007.
NIH Fellowships JoyAnn Phillips Rohan, PhD Postdoctoral Fellow Office of Minority Health and Health Disparities Georgetown University.

NIH Fellowships JoyAnn Phillips Rohan, PhD Postdoctoral Fellow Office of Minority Health and Health Disparities Georgetown University.
Mentor-Mentee Training Series TopicSpeaker(s)Date/Location Resources Marc Chimowitz, Mary Mauldin12/12/12 5-6pm Grants & Contracts: Not Just NIH Joann.

Mentor-Mentee Training Series TopicSpeaker(s)Date/Location Resources Marc Chimowitz, Mary Mauldin12/12/12 5-6pm Grants & Contracts: Not Just NIH Joann.
Career Opportunities and Education in Biomedical Informatics Webinar Presented by: William Hersh, MD Runtime: 30 Minutes Date: January 31, 2013.

Career Opportunities and Education in Biomedical Informatics Webinar Presented by: William Hersh, MD Runtime: 30 Minutes Date: January 31, 2013.
1 Harvard Postgraduate Educational Program in Clinical/Translational Science Presentation to ETEC May 6, 2009.

1 Harvard Postgraduate Educational Program in Clinical/Translational Science Presentation to ETEC May 6, 2009.
Training and Working at the National Institutes of Health Dr. Sharon L. Milgram, Director NIH Office of Intramural Training & Education.

Training and Working at the National Institutes of Health Dr. Sharon L. Milgram, Director NIH Office of Intramural Training & Education.
Science at the FDA: Update for the Science Board Jesse L. Goodman, MD, MPH Chief Scientist and Deputy Commissioner for Science and Public Health November.

Science at the FDA: Update for the Science Board Jesse L. Goodman, MD, MPH Chief Scientist and Deputy Commissioner for Science and Public Health November.
Overview of the Continuing Umbrella of Research Experiences (CURE) Grant Mechanisms Dr. Peter Ogunbiyi Diversity Training Branch Center to Reduce Cancer.

Overview of the Continuing Umbrella of Research Experiences (CURE) Grant Mechanisms Dr. Peter Ogunbiyi Diversity Training Branch Center to Reduce Cancer.
CAREER DEVELOPMENT  Career Development Program for Early and Mid-Career Women Faculty  Workshops  Roundtables  Mini-Mentoring Sessions.

CAREER DEVELOPMENT  Career Development Program for Early and Mid-Career Women Faculty  Workshops  Roundtables  Mini-Mentoring Sessions.
Johns Hopkins Technology Transfer 1 Translational Biomedical Research: Moving Discovery from Academic Centers to the Community Translational Biomedical.

Johns Hopkins Technology Transfer 1 Translational Biomedical Research: Moving Discovery from Academic Centers to the Community Translational Biomedical.

Similar presentations

Ads by Google