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Lesions of the Avian Pancreas
Robert E. Schmidt, DVM, PhD, DACVP, Drury R. Reavill, DVM, DABVP (Avian Practice), DACVP Veterinary Clinics: Exotic Animal Practice Volume 17, Issue 1, Pages 1-11 (January 2014) DOI: /j.cvex Copyright © 2014 Elsevier Inc. Terms and Conditions
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Fig. 1 Pancreatic atrophy. There is almost complete loss of zymogen and acinar cells are small with clear cytoplasm (H&E, 70×). Veterinary Clinics: Exotic Animal Practice , 1-11DOI: ( /j.cvex ) Copyright © 2014 Elsevier Inc. Terms and Conditions
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Fig. 2 Severe vacuolar degeneration of pancreatic exocrine cells attributed to zinc toxicity (H&E, 28×). Veterinary Clinics: Exotic Animal Practice , 1-11DOI: ( /j.cvex ) Copyright © 2014 Elsevier Inc. Terms and Conditions
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Fig. 3 Acute pancreatic necrosis in a Quaker parakeet.
Veterinary Clinics: Exotic Animal Practice , 1-11DOI: ( /j.cvex ) Copyright © 2014 Elsevier Inc. Terms and Conditions
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Fig. 4 Microscopic appearance of acute pancreatic necrosis. There is severe coagulative necrosis of the pancreas (left) adjacent to the small intestine (H&E, 70×). Veterinary Clinics: Exotic Animal Practice , 1-11DOI: ( /j.cvex ) Copyright © 2014 Elsevier Inc. Terms and Conditions
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Fig. 5 Severe chronic pancreatic fibrosis. Remaining acinar are small and separated by fibrous connective tissue (H&E, 70×). Veterinary Clinics: Exotic Animal Practice , 1-11DOI: ( /j.cvex ) Copyright © 2014 Elsevier Inc. Terms and Conditions
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Fig. 6 Chronic lymphocytic pancreatitis associated with paramyxovirus-3 infection. Veterinary Clinics: Exotic Animal Practice , 1-11DOI: ( /j.cvex ) Copyright © 2014 Elsevier Inc. Terms and Conditions
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Fig. 7 Herpesvirus-induced pancreatic necrosis and characteristic intranuclear inclusion bodies (arrows) (H&E, 280×). Veterinary Clinics: Exotic Animal Practice , 1-11DOI: ( /j.cvex ) Copyright © 2014 Elsevier Inc. Terms and Conditions
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Fig. 8 Poxvirus infection of the pancreas resulting in swollen acinar cells containing eosinophilic inclusion bodies (H&E, 70×). Veterinary Clinics: Exotic Animal Practice , 1-11DOI: ( /j.cvex ) Copyright © 2014 Elsevier Inc. Terms and Conditions
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Fig. 9 Pancreatic fluke infestation in a king parrot. Note atrophy and generalized roughening of the pancreas. Veterinary Clinics: Exotic Animal Practice , 1-11DOI: ( /j.cvex ) Copyright © 2014 Elsevier Inc. Terms and Conditions
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Fig. 10 Pancreatic carcinoma infiltrating into the wall of the small intestine. Veterinary Clinics: Exotic Animal Practice , 1-11DOI: ( /j.cvex ) Copyright © 2014 Elsevier Inc. Terms and Conditions
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Fig. 11 Pancreatic carcinoma. Note irregular, poorly defined acinar structures comprised of poorly differentiated epithelial cells. Veterinary Clinics: Exotic Animal Practice , 1-11DOI: ( /j.cvex ) Copyright © 2014 Elsevier Inc. Terms and Conditions
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Fig. 12 Severe vacuolation of islets of Langerhans in a cockatiel with clinical diabetes mellitus (H&E, 70×). Veterinary Clinics: Exotic Animal Practice , 1-11DOI: ( /j.cvex ) Copyright © 2014 Elsevier Inc. Terms and Conditions
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Fig. 13 Foci of hyperplasia of islets of Langerhans in an African Gray parrot (arrows) (H&E, 70×). Veterinary Clinics: Exotic Animal Practice , 1-11DOI: ( /j.cvex ) Copyright © 2014 Elsevier Inc. Terms and Conditions
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Fig. 14 Immunohistochemical stain for glucagon. Cells positive are brown, indicating primarily A cells undergoing the hyperplastic change (Immunoperoxidase stain for Glucagon, 70×). Veterinary Clinics: Exotic Animal Practice , 1-11DOI: ( /j.cvex ) Copyright © 2014 Elsevier Inc. Terms and Conditions
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Fig. 15 Carcinoma of the islets of Langerhans. Note formation of infiltrative nests of poorly differentiated islet cells through the capsule and into surrounding pancreatic parenchyma (H&E, 70×). Veterinary Clinics: Exotic Animal Practice , 1-11DOI: ( /j.cvex ) Copyright © 2014 Elsevier Inc. Terms and Conditions
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