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Intraoperative frozen section analysis of sentinel lymph nodes in breast carcinoma patients in a tertiary hospital in Pakistan  Ambreen Moatasim, Shafaq.

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Presentation on theme: "Intraoperative frozen section analysis of sentinel lymph nodes in breast carcinoma patients in a tertiary hospital in Pakistan  Ambreen Moatasim, Shafaq."— Presentation transcript:

1 Intraoperative frozen section analysis of sentinel lymph nodes in breast carcinoma patients in a tertiary hospital in Pakistan  Ambreen Moatasim, Shafaq Mujtaba, Naveen Faridi  International Journal of Surgery  Volume 11, Issue 3, Pages (April 2013) DOI: /j.ijsu Copyright © 2013 Surgical Associates Ltd Terms and Conditions

2 Fig. 1 Serial slicing and processing of a sentinel lymph node for frozen section. International Journal of Surgery  , DOI: ( /j.ijsu ) Copyright © 2013 Surgical Associates Ltd Terms and Conditions

3 Fig. 2 Subcapsular micrometastasis, confirmed on immunohistochemistry using cytokeratin AE1/AE3 (H&EX10M). Inset showing infiltrating ductal carcinoma Grade 2 as seen on paraffin section of breast lump of same patient. International Journal of Surgery  , DOI: ( /j.ijsu ) Copyright © 2013 Surgical Associates Ltd Terms and Conditions

4 Fig. 3 A large focus of metastatic carcinoma (arrow). Effacement of nodal architecture on the left by cords and sheets of tumor cells having pleomorphic, hyperchromatic nuclei (H&EX10M). Inset showing infiltrating ductal carcinoma Grade 2 on paraffin section of breast lump of same patient.. International Journal of Surgery  , DOI: ( /j.ijsu ) Copyright © 2013 Surgical Associates Ltd Terms and Conditions

5 Fig. 4 Micrometastasis (arrows) in a sentinel lymph node. (a) A suspicious focus seen on frozen section (H&EX4M), (b) On high power (H&EX20M) cords and groups of tumor cells seen in subcapsular area. International Journal of Surgery  , DOI: ( /j.ijsu ) Copyright © 2013 Surgical Associates Ltd Terms and Conditions


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