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The antileukemic activity of Δ12-PGJ3

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Presentation on theme: "The antileukemic activity of Δ12-PGJ3"— Presentation transcript:

1 The antileukemic activity of Δ12-PGJ3
by Paul A. Ney Blood Volume 118(26): December 22, 2011 ©2011 by American Society of Hematology

2 Antileukemic activity of eicosapentaenoic acid (EPA)–derived cyclopentenone prostaglandins.
Antileukemic activity of eicosapentaenoic acid (EPA)–derived cyclopentenone prostaglandins. Left panel shows a liquid chromatography-UV trace of EPA-derived metabolites endogenously produced by macrophages. Right panel demonstrates the selective antileukemic effect of Δ12-PGJ3 on BCR-ABL–transformed leukemic stem cells. Paul A. Ney Blood 2011;118: ©2011 by American Society of Hematology


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