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New Therapies for Hyperkalemia Across the Continuum of Care

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Presentation on theme: "New Therapies for Hyperkalemia Across the Continuum of Care"— Presentation transcript:

1 New Therapies for Hyperkalemia Across the Continuum of Care

2

3 Overview of Hyperkalemia

4 RAAS Inhibitor Use and Risk of Hyperkalemia

5 Diagnostic Workup Causes of Hyperkalemia

6 Diagnostic Workup Electrocardiographic Features

7 Acute Treatment of Hyperkalemia

8 Increasing Incidence of Hyperkalemia

9 Dietary Management of Hyperkalemia

10 Management of Chronic Hyperkalemia Before Era of New K+ Binders

11 SPS

12 Challenges of Hyperkalemia in At-Risk Patients

13 Summary

14 New K+ Binder Patiromer

15 Efficacy of Patiromer Maintains Normal K+ Levels Up to 1 Year

16 Emerging K+ Binder Sodium Zirconium Cyclosilicate (ZS-9)

17 Efficacy of ZS-9 During 48-h Induction Phase in HARMONIZE

18 HARMONIZE Efficacy During Randomized Phase

19 ZS005 Interim Results ZS-9 Maintains Normal K+ Levels Up to 1 Year

20 K+ and Na+ Concentrations in the GI Tract

21 SPS (cont)

22 SPS Plus Sorbitol vs Sorbitol Alone

23 New K+ Binders Adverse Events

24 Comparison of SPS, Patiromer, and ZS-9

25 New K+ Binders as Preventative Therapy

26 Closing Comments

27 Abbreviations


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