1. Innovative Insulin Combinations: A New strategy for the Person With T2DM

3. Program Overview

4. Current Gaps in Insulin Therapy

5. The Role of Basal Insulin

6. Treatment Gaps Related to Titration

7. Patient-Led Titration of Insulin

8. Clinical Inertia

9. Intensification of Insulin

10. Premixed Insulins

11. Basal-Bolus Therapy

12. GLP-1 RA Mechanism of Action

13. Basal Insulin Plus GLP-1 RA—Free Combination

14. Basal Insulin/GLP-1 RA—Fixed-Ratio Combination

15. Formulations—Fixed-Ratio Basal Insulin/GLP-1 RA Combinations

16. DUAL V: Study Design

17. DUAL V: Key Results

18. DUAL V: Adverse Events

19. LixiLan-L Trial: Study Design

20. LixiLan-L Trial: Key Clinical Findings

21. LixiLan-L Trial: Key Clinical Findings (cont)

22. Potential Challenges With Fixed-Ratio Combinations

23. Fixed-Ratio Combination Basal Insulin/GLP-1 RA in Clinical Practice

24. Summary

25. Abbreviations