1. Chapter 7 “Cellular Respiration”
Glycolysis & Fermentation
Aerobic Respiration
AKA OXIDATION OF GLUCOSE

2. Cellular Respiration Overview
A process where organisms break down food to make ATP
EVERYONE DOES IT!!!
Overall Reaction:
C6H12O6+6O2  6CO2+6H2O+Energy (ATP)
Anaerobic Path (no O2), 2 Steps: net 2 ATP
Not efficient
Glycolysis
Fermentation: Lactic Acid or Alcoholic
Aerobic Path (O2), 3 Steps: net 36 ATP
Krebs cycle
Electron Transport Chain

3. Overview, cont.
2 ATP
36 ATP

4. Glycolysis Location: cytoplasm Products: 2 pyruvate (3-C)
2 NADH (e- acceptors)
4 ATP – 2 ATP used
= 2 ATP net
NEXT STEP VARIES IF 02 IS PRESENT OR ABSENT

5. Fermentation: Without O2
Lactic Acid
Location: cytoplasm
Products:
Regenerates NAD+
Uses:
Food production: cheese & yogurt
Muscle cells (i.e. sprint)
Alcoholic
Location: cytoplasm
Products:
Regenerate NAD+
Ethyl Alcohol
CO2
Yeast & some plant cells
Uses:
Wine & beer
Bread making

6. Lactic Acid Fermentation

7. Alcoholic Fermentation

8. Quick Review

9. Aerobic Respiration (O2) Overview
2 Steps:
Krebs Cycle (KC)
Electron transport chain (ETC)
Location:
Prokaryotes: KC & ETC in cytosol
Eukaryotes:
KC: mitochondrial matrix
ETC: inner mitochondrial membrane
Products:
KC: 6NADH, 2FADH2, 2ATP, 4CO2
ETC: 34 ATP

10. Mitochondrion

11. Krebs Cycle Start: Pyruvic Acid (PA) enters matrix
PA + Acetyl Coenzyme A Acetyl CoA (2-C) & CO2
Yields NADH
Transition Step

12. Stop! Let’s Do Some Accounting Work!
Step
Molecule
How Many
Glycolysis
NADH
ATP
Transition
CO2
Krebs
FADH2
ETC
??????????????????????

13. Electron Transport Chain
NADH & FADH2 release H+ & e- to make ATP
e- released energy pump H+ between 2 membranes
Chemiosmosis: generates ATP
O2 final electron acceptor + e- + H+ Produces H2O
Regenerate NAD+ & FAD

14. “Cash In Values”
Each NADH = 3 ATP
Each FADH2 = 2 ATP

15. Energy Yield/ Efficiency
Calculations!!