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Volume 134, Issue 4, Pages (April 2008)

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1 Volume 134, Issue 4, Pages 945-952 (April 2008)
Gastric Cancer Risk in Patients With Premalignant Gastric Lesions: A Nationwide Cohort Study in the Netherlands  Annemarie C. de Vries, Nicole C.T. van Grieken, Caspar W.N. Looman, Mariël K. Casparie, Esther de Vries, Gerrit A. Meijer, Ernst J. Kuipers  Gastroenterology  Volume 134, Issue 4, Pages (April 2008) DOI: /j.gastro Copyright © 2008 AGA Institute Terms and Conditions

2 Figure 1 The proportion of patients with atrophic gastritis, intestinal metaplasia, and dysplasia receiving 1 or more follow-up upper-gastrointestinal endoscopies. Gastroenterology  , DOI: ( /j.gastro ) Copyright © 2008 AGA Institute Terms and Conditions

3 Figure 2 The proportion of patients with atrophic gastritis, intestinal metaplasia, and dysplasia receiving histological follow-up according to 5-year age categories. Gastroenterology  , DOI: ( /j.gastro ) Copyright © 2008 AGA Institute Terms and Conditions

4 Figure 3 Timing of re-examination in patients who received histological re-evaluation of premalignant gastric lesions. Gastroenterology  , DOI: ( /j.gastro ) Copyright © 2008 AGA Institute Terms and Conditions

5 Figure 4 Follow-up results in patients in whom histological re-evaluation was performed. The results are presented as most advanced gastric lesion during follow-up for each category of premalignant gastric lesions at baseline. The outcome of patients who developed esophageal or cancer at the esophagogastric junction is not mentioned in this figure. Mean length of follow-up for patients with atrophic gastritis, intestinal metaplasia, mild-to-moderate dysplasia, and severe dysplasia: 3.5, 2.8, 2.5, and 1.0 years, respectively. Gastroenterology  , DOI: ( /j.gastro ) Copyright © 2008 AGA Institute Terms and Conditions

6 Figure 5 Progression rate of premalignant gastric lesions to gastric cancer in 92,250 patients with premalignant gastric lesions (90,780 censored patients). Gastroenterology  , DOI: ( /j.gastro ) Copyright © 2008 AGA Institute Terms and Conditions

7 Figure 6 Progression from intestinal metaplasia to gastric adenocarcinoma after 10 years’ follow-up within the same patient. (A) Gastric mucosa (corpus) showing mild gastritis with marked intestinal metaplasia, no dysplasia (1993). (B) Gastric mucosa (angulus) showing moderately differentiated gastric adenocarcinoma (2003). H&E staining, original magnification x100. Gastroenterology  , DOI: ( /j.gastro ) Copyright © 2008 AGA Institute Terms and Conditions


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