1. Warm-up Problem: Autosomal Recessive
Steve and Linda have a history of cystic fibrosis in their families. Steve is a healthy carrier and Linda is heterozygous. They always wanted a family with three children (make the children any gender you wish).
Linda
Complete a Pedigree showing these 5 people.
Complete a Punnett square for Steve & Linda.
What is the probability for having a healthy child?
What is the probability that all three children will be healthy?
Steve Hh Hh
¾ healthy
Steve
¾ healthy
Linda
¾ healthy
Steve H h
3/4 H
Steve HH Hh
Key
H = healthy
h = cystic fibrosis h Hh hh
27/64

2. Warm-up Problem: Autosomal Dominance
Rodney recently tested negative for the FH gene even though his mother and father had FH. Francine recently survived a heart attack at 34 years of age. They have two children who were recently tested negative for the FH gene.
Complete a Pedigree showing these 6 people.
Complete a Punnett square for Rodney & Francine.
What is the probability for having a healthy child?
What were the odds of Rodney being born without the FH gene? h Hh Hh H h
Steve Hh Hh hh hh
Francine
Francine
Rodney hh Hh
50% hh hh
25%
Key
H = FH disorder h = healthy

3. Warm-up Problem: Autosomal Recessive
Steve and Linda have a history of cystic fibrosis in their families. Steve is a healthy carrier and Linda is heterozygous. They always wanted a family with three children (make the children any gender you wish).
Complete a Pedigree showing these 5 people.
Complete a Punnett square for Steve & Linda.
What is the probability for having a healthy child?
What is the probability that all three children will be healthy?

4. Warm-up Problem: Autosomal Recessive
Steve and Linda have a history of cystic fibrosis in their families. Steve is a healthy carrier and Linda is heterozygous. They always wanted a family with three children (make the children any gender you wish).
Complete a Pedigree showing these 5 people.
Complete a Punnett square for Steve & Linda.
What is the probability for having a healthy child?
What is the probability that all three children will be healthy?

5. Warm-up Problem: Autosomal Dominance
Rodney recently tested negative for the FH gene even though his mother and father had FH. Francine recently survived a heart attack at 34 years of age. They have two children who were recently tested negative for the FH gene.
Complete a Pedigree showing these 6 people.
Complete a Punnett square for Rodney & Francine.
What is the probability for having a healthy child?
What were the odds of Rodney being born without the FH gene?

6. Warm-up Problem: Autosomal Dominance
Rodney recently tested negative for the FH gene even though his mother and father had FH. Francine recently survived a heart attack at 34 years of age. They have two children who were recently tested negative for the FH gene.
Complete a Pedigree showing these 6 people.
Complete a Punnett square for Rodney & Francine.
What is the probability for having a healthy child?
What were the odds of Rodney being born without the FH gene?