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Muir-Torre Phenotype Has a Frequency of DNA Mismatch-Repair-Gene Mutations Similar to That in Hereditary Nonpolyposis Colorectal Cancer Families Defined.

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Presentation on theme: "Muir-Torre Phenotype Has a Frequency of DNA Mismatch-Repair-Gene Mutations Similar to That in Hereditary Nonpolyposis Colorectal Cancer Families Defined."— Presentation transcript:

1 Muir-Torre Phenotype Has a Frequency of DNA Mismatch-Repair-Gene Mutations Similar to That in Hereditary Nonpolyposis Colorectal Cancer Families Defined by the Amsterdam Criteria  Roland Kruse, Arno Rütten, Christof Lamberti, Hamid Reza Hosseiny-Malayeri, Yaping Wang, Corina Ruelfs, Matthias Jungck, Micaela Mathiak, Thomas Ruzicka, Wolfgang Hartschuh, Michele Bisceglia, Waltraut Friedl, Peter Propping  The American Journal of Human Genetics  Volume 63, Issue 1, Pages (July 1998) DOI: /301926 Copyright © 1998 The American Society of Human Genetics Terms and Conditions

2 Figure 1 MIN in patients MTS-K10 and MTS-K1a. DNA from peripheral blood (lanes N) and skin tumor tissues (lane T, sebaceous epithelioma; lane T1, sebaceous adenoma; and lane T2, sebaceous epithelioma) was examined by use of microsatellite marker D21S171 and was visualized by autoradiography after separation on a denaturing gel. The American Journal of Human Genetics  , 63-70DOI: ( /301926) Copyright © 1998 The American Society of Human Genetics Terms and Conditions


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